Life Sciences Commons^™

Brain Α-Tocopherol Concentration Is Inversely Associated With Neurofibrillary Tangle Counts In Brain Regions Affected In Earlier Braak Stages: A Cross-Sectional Finding In The Oldest Old, J. Tanprasertsuk, T.M. Scott, M.A. Johnson, L.W. Poon, P.T. Nelson, A. Davey, J.L. Woodard, R. Vishwanathan, A.K. Barbey, K. Barger, X.-D. Wang, E.J. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Objectives: Higher vitamin E status has been associated with lower risk of Alzheimer’s disease (AD). However, evidence of the association of vitamin E concentration in neural tissue with AD pathologies is limited. Design: The cross-sectional relationship between the human brain concentrations of α- and γ-tocopherol and the severity of AD pathologies – neurofibrillary tangle (NFT) and neuritic plaque (NP) – was investigated. Setting & Participants: Brains from 43 centenarians (≥ 98 years at death) enrolled in the Phase III of the Georgia Centenarian Study were collected at autopsy. Measurements: Brain α- and γ-tocopherol concentrations (previously reported) …

Availability And Consumption Of Vitamin A Foods Among Southern Ethiopian And Zambian Primary Students, Trang Vuong

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Understand vitamin A food availability in open-air markets (OAM’s), and consumption of those foods by primary school children in southern Ethiopia/Zambia.

Methods: Conducted inventories of all consumable/potable items and interviewed 6-7th grade students about consumption of items with vitamin A.

Results: Students consumed most of the 14 vitamin A foods/items sold in OAM’s. Zambian students ate more liver, pumpkin, squash, watermelon, and wild fruits, while Ethiopian students almost never consumed squash, watermelon or wild fruits.

Conclusions: The availability of Vitamin A foods in Ethiopian and Zambian OAMs are varied; however, Zambian children reportedly eat more vitamin A foods. Nutrition …

Determinants Of Gluten-Free Diet Adoption Among Individuals Without Celiac Disease Or Non-Celiac Gluten Sensitivity, Kristina Arslain, Christopher Gustafson, Pratiksha Baishya, Devin Rose

Department of Agricultural Economics: Faculty Publications

Objectives: Gluten free (GF) foods are typically less nutritious and more expensive than their gluten-containing variants, yet people without a diagnosed gluten sensitivity continue to adopt this diet. There is a lack of research about what factors drive people without Celiac disease or non-Celiac gluten sensitivity to follow the GF diet. Methods: A nationally representative sample of 2982 US residents without a diagnosed gluten sensitivity were surveyed about their attitudes, perceptions, and experiences with the GF diet. Logistic regression was used to compare respondents who were currently avoiding or had avoided gluten previously (GF consumer) to respondents who had never …

Metabolic Benefits Of Plant-Based N-3 Polyunsaturated Fatty Acids On Brown Thermogenesis, Kyung Ho Park

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

There are two essential fatty acids for humans, a-linolenic acid (ALA) and linoleic acid (LA), which should be taken from foods to maintain health. Once incorporated into cells, ALA and LA, which are omega-3 poly unsaturated fatty acid (n-3 PUFA) and n-6 PUFA respectively, undergo elongation and desaturation to generate longer and more unsaturated fatty acids influencing inflammation and immunological responses. Numerous studies showed a dietary reduction of n-6/n-3 PUFA ratio improves cardiovascular health, inflammation, and insulin resistance. Fish oil, the main resource for n-3 PUFA, is shown to increase these health benefits. In our lab, we investigated the efficacy …

Grains, Grasses, And Tubers: Staple Carbohydrates In The Diets Of Middle School Children Of Southern Zambia And Ethiopia, Brianna Juma

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Survey staple carbohydrate availability in local markets, complete anthropometric assessment, and interview primary school children about carbohydrate consumption in Southern Zambia and Ethiopia

Methods: Market inventories, anthropometric assessments, and interviews of 6th and 7th grade students

Results: Ethiopians have a greater diversity of available carbohydrates, have better overall anthropometric values compared to Zambian children, and consume more nutritious and varied carbohydrate types.

Conclusions: Diversity in carbohydrate availability and consumption, as well as more nutritious options, are associated with healthier growth rates among primary school children in Southern regions of Zambia and Ethiopia.

Microrna-Mrna Co-Sequencing Identifies Transcriptional And Post-Transcriptional Regulatory Networks Underlying Muscle Wasting In Cancer Cachexia, Geysson Javier Fernandez, Juarez Henrique Ferreira, Ivan Jose Vechetti Jr, Leonardo Nazario De Moraes, Sarah Santiloni Cury, Paula Paccielli Freire, Jayson Gutierrez, Renato Ferretti, Maeli Dal-Pai-Silva, Silvia Regina Rogatto, Robson Francisco Carvalho

Department of Nutrition and Health Sciences: Faculty Publications

Cancer cachexia is a metabolic syndrome with alterations in gene regulatory networks that consequently lead to skeletal muscle wasting. Integrating microRNAs mRNAs omics profiles offers an opportunity to understand transcriptional and post-transcriptional regulatory networks underlying muscle wasting. Here, we used RNA sequencing to simultaneously integrate and explore microRNAs and mRNAs expression profiles in the tibialis anterior (TA) muscles of the Lewis Lung Carcinoma (LLC) model of cancer cachexia. We found 1,008 mRNAs and 18 microRNAs differentially expressed in cachectic mice compared with controls. Although our transcriptomic analysis demonstrated a high heterogeneity in mRNA profiles of cachectic mice, we identified a …

Energy And Amino Acid Metabolism In Lactating Jersey Cows Consuming Feed Byproducts, Kyle Mclain

Department of Animal Science: Dissertations, Theses, and Student Research

Animal protein byproducts are high bypass proteins commonly used in the dairy industry. These bypass proteins can escape the rumen to supply additional amino acids needed to support milk and protein yield. Two of the more popular animal protein byproducts used in the dairy industry are blood meal and hydrolyzed feather meal. In the first experiment, two flow meters were compared using headbox-style calorimeters. The objectives of the first study were to test mass flow meter (MFM) and volumetric flow meter (VFM) by measuring O2 consumption and CO2 production and to illustrate the effects of incomplete gas recovery on estimated …

Protein Availability And Consumption, And Stunting Rates, For Primary School Children In The Southern Regions Of Ethiopia And Zambia, Megan Wackel

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

•Stunting is common in Sub-Sahara Africa, with millions of children who are short in stature also experiencing poor overall health and development, as well as poor school performance (Semba 2016; Semba, et al., 2016). •As many as 39% of children under 5 years of age in Ethiopia’s Sidama Region (formerly SNNPR) can be classified as stunted (CSA & ICF 2016). By comparison, 29% of under 5’s in Zambia’s Southern Province have short height for age (CSA, MOH, & ICF 2018). •Low protein and essential amino acid intake, among populations of 116 countries, has been suggested as the primary cause of …

A Qualitative Analysis Of The Barriers Faced By Nursing Assistants And Medication Aides In The Care Of Dysphagia Residents, Lauren Kreuzberg

Honors Theses

Dysphagia refers to the symptom of difficulty in swallowing that accompanies several prevalent conditions in the older adult population, including amyotrophic lateral sclerosis (ALS, Lou Gehrig’s Disease), stroke, Parkinson’s Disease, Multiple Sclerosis, dementia, various cancers, and brain tumors (Allari, 2014). Many older adults who suffer from these conditions reside in nursing facilities, where most of their care is provided by certified nursing assistants (CNAs) and medication aides (MAs). However, the extent of these workers’ knowledge and competence in providing care to nursing home residents with dysphagia is vastly under-researched. The qualitative analysis investigates themes among interviews with fifteen CNAs and …

Zika Virus Induces Apoptosis In Retinal Pigmented Epithelial Cells, Madison Kraus, Philma Glora Muthuraj, Sathish Kumar Natarajan

UCARE Research Products

Zika virus is a single-stranded positive sense RNA virus that attracted international attention in 2015 when an epidemic broke out in Brazil. This vector borne virus is transmitted by mosquitos and is especially concerning for pregnant women because the virus can affect the development of the fetus. One known complication is the destruction of infected retinal epithelial cells. The transduction of light is interrupted due to cell death and results in blind spots. Previous research has demonstrated that palmitoleate can reduce the observed levels of apoptosis in ZIKAV infected JEG-3 cells. We have also seen the protection of retinal pigmented …

Use Of A Novel Whole-Body Imaging Approach To Predict Resting Metabolic Rates In Athletes, Nicole Vencil

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Prediction of energy expenditure allows for calculation of appropriate energy requirements, which is especially important for athletes. Resting metabolic rate (RMR) is the greatest contributor to total daily energy expenditure (TDEE) and is typically measured via indirect calorimetry. Indirect calorimetry is not always available, which results in the need for predictive equations. Most predictive equations have been developed with participants resembling the general population and have not been found to be appropriate for athletes, as they may incorrectly predict RMR due to the unique differences of body composition between athletes and the general population. The purpose of the present study …

Stunting And Infectious Disease In Ethiopian And Zambian Children, Alyssa Arndt

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

PURPOSE: To evaluate whether children who are malnourished/stunted are more likely to have experienced infectious disease.

METHODS: 6th and 7th students (n=546) were interviewed about health history and assessed using anthropometry.

RESULTS: Children who are short for their age also have higher rates of stunting. Malaria is the most experienced infectious disease.

CONCLUSIONS: Given that malaria was the most common infectious disease experience listed among middle school children, and that those who have experienced disease are more likely to be stunted, increased malaria prevention methods may improve the long-term health of Ethiopian and Zambian schoolchildren.

Mothers’ Experience With Infant Complementary Feeding Practices: A Phenomenological Study., Tyler Martin

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Background. Complementary feeding practices include what, when, and how to feed (Birch and Doub, 2014). The gradual transition from feeding exclusively human milk, formula milk, or a combination of both to complementary foods over the first 24 months of life is necessary to ensure proper growth and development (Dewey, 2001; Pearce & Langley-Evans, 2013). While research does exist on complementary feeding, such as infant diet composition, limited research exists on exploring complementary feeding practices from first-time mothers’ experiences.

Methods. This study utilized transcendental phenomenological qualitative research methodology. A pilot tested semi-structured interview guide was used to examine demographics as …

Racial-Ethnic Disparities In Prediabetes And Diabetes Among Us Adults, Carly Selleck, Jennifer R. Mcatee, Weiwen Chai

UCARE Research Products

Type-2 diabetes is a chronic metabolic disease affecting more than3 4 million Americans or 10.5% of the population [1]. While almost 90% of people are not aware of their prediabetes status, around 88 million adults are considered to be prediabetic [2]. Without any prevention methods, 70% of prediabetes cases will eventually develop into diabetes[3]. While the development of type-2 diabetes is multifactorial, lifestyle factors such as diet and physical activity as well as socioeconomic (SES) factors such as poverty and education can be main contributors [4]. This study aimed to assess racial-ethnic differences in SES, lifestyle factors and prevalence of …

Caloric Restriction Induces Anabolic Resistance To Resistance Exercise, Chaise Murphy, Karsten Koehler

Department of Nutrition and Health Sciences: Faculty Publications

Purpose Weight loss can result in the loss of muscle mass and bone mineral density. Resistance exercise is commonly prescribed to attenuate these effects. However, the anabolic endocrine response to resistance exercise during caloric restriction has not been characterized. Methods Participants underwent 3-day conditions of caloric restriction (15 kcal kg FFM⁻¹) with post-exercise carbohydrate (CRC) and with post-exercise protein (CRP), and an energy balance control (40 kcal kg FFM⁻¹) with post-exercise carbohydrate (CON). Serial blood draws were taken following five sets of five repetitions of the barbell back squat exercise on day 3 of each condition. …

Protective Role Of Shiitake Mushroom-Derived Exosome-Like Nanoparticles In D-Galactosamine And Lipopolysaccharide-Induced Acute Liver Injury In Mice, Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D. Kachman, Sathish Kumar Natarajan, Jiujiu Yu

Department of Nutrition and Health Sciences: Faculty Publications

Fulminant hepatic failure (FHF) is a rare, life-threatening liver disease with a poor prognosis. Administration of D-galactosamine (GalN) and lipopolysaccharide (LPS) triggers acute liver injury in mice, simulating many clinical features of FHF in humans; therefore, this disease model is often used to investigate potential therapeutic interventions to treat FHF. Recently, suppression of the nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome, was shown to alleviate the severity of GalN/LPS-induced liver damage in mice. Therefore, the goal of this study was to find dietary exosome-like nanoparticles (ELNs) with therapeutic potential in curbing FHF by …

Healthy Pregnancies And Essential Fats: Focus Group Discussions With Zambian Women On Dietary Need And Acceptability Of A Novel Rusf Containing Fish Oil Dha, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, Concetta C. Dirusso

Department of Nutrition and Health Sciences: Faculty Publications

Background: Nut butter-based Ready to Use Supplemental Foods (RUSF) are an effective way to add nutrients and calories to diets of malnourished and food insecure populations. The RUSF formulations have been further modified to add micronutrients including iron and folic acid needed during pregnancy and lactation. Because docosahexaenoic acid (DHA, C22:6 n-3) enhances fetal development and birth outcomes, it has been suggested that perhaps RUSF formulations for pregnancy should also include this Omega 3 fatty acid. The goal of the present study was to gain an understanding of Zambian women’s knowledge of nutritional needs in pregnancy through structured focus group …

The Effects Of Asparagus Racemosus Supplementation Plus 8 Weeks Of Resistance Training On Muscular Strength And Endurance, John Paul V. Anders, Joshua L. Keller, Cory M. Smith, Ethan C. Hill Phd, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Previous studies have demonstrated that ayurvedic ingredients exhibit ergogenic (performance enhancing) properties, however, no previous studies have examined the ergogenic potential of Asparagus racemosus. The purpose of the present study was to examine the ergogenic efficacy of supplementation with 500 mg·d−1 of A. racemosus during bench press training. Eighteen recreationally trained men (mean ± SD; age = 20.4 ± 0.5 yrs; height = 179.7 ± 1.5 cm; weight = 84.7 ± 5.7 kg) were randomly assigned either 500 mg·d−1 of A. racemosus (n = 10) or placebo (n = 8). An overlapping sample of 10 participants were used to determine …

Alpha-Linolenic Acid-Enriched Butter Promotes Fatty Acid Remodeling And Thermogenic Activation In The Brown Adipose Tissue, Mikyoung You, Rong Fan, Judy Kim, Seung-Ho Shin, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Supplementation with n-3 long-chain (LC) polyunsaturated fatty acids (PUFA) is known to promote thermogenesis via the activation of brown adipose tissue (BAT). Agricultural products that are biofortified with α-linolenic acid (ALA), the precursor of n-3 LC PUFA, have been launched to the market, but their impact on BAT function is unknown. This study aimed to evaluate the effects of ALA-biofortified butter on lipid metabolism and thermogenic functions in the BAT. C57BL/6 mice were fed a high-fat diet containing ALA-biofortified butter (n3Bu, 45% calorie from fat) for ten weeks in comparison with the isocaloric high-fat diets prepared from conventional butter or …

Dental Health Factors Among Primary School Children In Southern Regions Of Ethiopia And Zambia, Gisselle Hernandez

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Assess oral health status, and factors affecting oral health, among primary schoolchildren in southern Ethiopia and Zambia. Methods: Visual dental assessments, anthropometric measurements, and questionnaires used to collect data among 6th and 7th grade students. Results: Although stunting rates were nearly equal, decay rates were not; 17.51% of Zambian students and 47.27% of Ethiopian students had one or more decayed teeth. Ethiopian students with dental fluorosis (74.55%) had higher rates of decay than those without the condition (p < .05). There were also significant differences between Ethiopians and Zambians regarding use of dental hygiene tools: Ethiopians were more likely to use dental sticks, while Zambians employed toothbrushes for cleaning. Conclusions: Dental health and hygiene education, focused on unique socioecological settings, could improve the oral health status of Ethiopian and Zambian children.

PowerPoint file attached below

Nutrition And Attendance For Primary School Students In Ethiopia And Zambia, Lillie Tronnes

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Introduction: Nutrition impacts attendance for primary school students in Southern Ethiopia and Zambia. Food insecurity causes school-age children to be undernourished, malnourished, and stunted. These health concerns greatly impact ability to attend and perform in school.

Methods: Between May and June of 2019 6th and 7th grade students were surveyed within 4 schools in Ethiopia and 5 schools in Zambia. Anthropometric data, health history, and nutritional habits were surveyed.

Results: 8% of Ethiopian students were stunted while 10% of Zambian students were stunted. Ethiopian students indicated school lunch was an incentive while Zambian students did not. Most …

Endogenous Versus Exogenous Carbohydrate Oxidation Measured By Stable Isotopes In Pre-Pubescent Children Plus 13c Abundances In Foods Consumed Three Days Prior, Marni E. Shoemaker, Zachary M. Gillen, Brianna D. Mckay, Todd J. Leutzinger, Vikkie A. Mustad, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: The purposes of the present study were to (a) examine resting metabolism, substrate utilization, and endogenous versus exogenous carbohydrate (CHO) oxidation before and after 30-g rapidly-digesting carbohydrate (RDC) ingestion using indirect calorimetry and breath test analysis of stable isotope concentrations in pre-pubescent children and (b) report the 13C abundances in foods consumed for three days prior.

Methods: Nineteen children (n 1⁄4 10 boys, n 1⁄4 9 girls) at Tanner stage I or II participated (mean age ± 95% CI 1⁄4 9.84 ± 0.77 y) in this study. Food was administered to the children for three days preceding their scheduled …

Eb4cast Approach Improves Science Communication With Stakeholders In A College-Based Health Program, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Rahel A. Wattick, Wenjun Zhou, Tanya M. Horacek, Anne E. Mathews, Kendra K. Kattlemann, Tandalayo Kidd, Adrienne A. White, Onikia N. Brown, Jesse Stabile Morrell, Lisa Franzen-Castle, Karla P. Shelnutt, Carol Byrd-Bredbenner, Terezie Tolar-Peterson, Geoffrey W. Greene, Sarah E. Colby

Department of Nutrition and Health Sciences: Faculty Publications

Communicating scientific results with community partners is often lacking in intervention programs, thus eB4CAST was developed to facilitate impact sharing. This article investigated using the eB4CAST dissemination tool to communicate impact from a campus-based obesity prevention program. Data from Get Fruved RCT university sites collected at baseline were used to generate eB4CAST reports. Experts (n = 13) and RCT sites (n = 15) were asked to provide feedback on eB4CAST reports based on appeal, understanding, and clarity. On all Likert items, participants rated above 7 on each (out of 10). Positive responses from open-ended questions included eB4CAST reports being clear, …

Single-Arm, Non-Randomized, Time Series, Single-Subject Study Of Fecal Microbiota Transplantation In Multiple Sclerosis, Phillip A. Engen, Antonia Zaferiou, Heather Rasmussen, Ankur Ankub, Stefan J. Green, Louis F. Fogg, Christopher B. Forsyth, Shohreh Raeisi, Bruce Hamaker, Ali Keshavarzian

Department of Nutrition and Health Sciences: Faculty Publications

Emerging evidence suggests intestinal microbiota as a central contributing factor to the pathogenesis of Relapsing-Remitting-Multiple-Sclerosis (RRMS). This novel RRMS study evaluated the impact of fecal-microbiota-transplantation (FMT) on a broad array of physiological/clinical outcomes using deep metagenome sequencing of fecal microbiome. FMT interventions were associated with increased abundances of putative beneficial stool bacteria and short-chain-fatty-acid metabolites, which were associated with increased/improved serum brain-derived-neurotrophic-factor levels and gait/walking metrics. This proof-of-concept single-subject longitudinal study provides evidence of potential importance of intestinal microbiota in the pathogenesis of MS, and scientific rationale to help design future randomized controlled trials assessing FMT in RRMS patients.

Ipsilateral And Contralateral Torque Responses To Bilateral And Unilateral Maximal, Fatiguing, Isokinetic Leg Extensions, Tyler J. Neltner, John Paul V. Anders, Joshua L. Keller, Robert W. Smith, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Background: Few studies have compared performance fatigability (PF) for bilateral versus unilateral isokinetic tasks. Objectives: The purpose of this study was to examine: Mode- specific testing responses to isokinetic fatigue, differences in PF between bilateral and unilateral leg extensions, and the effects of fatiguing, unilateral, dynamic leg extensions on contralateral isokinetic peak torque (PT) and maximal voluntary isometric contraction (MVIC). Methods: Eight men (mean ± SD: age= 22.5 ± 2.5 yr.) completed pre- and post-testing for PT and MVIC following 50 bilateral, unilateral right or left leg maximal, isokinetic leg extensions at 180°·s-1, on three separate days. Fatigue-induced decreases in …

Application Of The Neuromuscular Fatigue Threshold Treadmill Test To Muscles Of The Quadriceps And Hamstrings, Clayton L. Camic, Attila J. Kovacs, Trisha A. Vandusseldorp, Ethan C. Hill, Evan A. Enquist

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: The purposes of the present study were: (1) to determine whether the physical working capacity at the fatigue threshold (PWCFT) model that has been used for estimating the onset of neuromuscular fatigue in the vastus lateralis (VL) during incremental treadmill running could also be applied to the vastus medialis (VM), biceps femoris (BF), and semitendinosus (ST) muscles; and (2) if applicable, to compare the running velocities associated with the PWCFT among these muscles.

Methods: Eleven subjects (age 21.7 § 1.8 years) performed an incremental treadmill test to exhaustion with electromyographic signals recorded from the VL, VM, BF, and ST. …

Iron-Rich Foods, Anemia, And Malaria In Primary School Children In Southern Ethiopia And Zambia, Julianne Fay

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

PURPOSE: To examine the relationship between iron-deficient anemia and malaria in primary school children in Southern Ethiopia and Zambia and assess the correlation between diet and health status.

METHODS: Market inventories, observations at health outposts, and interviews and anthropometric assessments of 6th and 7th grade students.

RESULTS: Both Ethiopia and Zambia had 20 iron-rich foods available in local markets. Only liver consumption was associated with malaria experience; those who consumed liver were significantly less likely to have had the disease (p

DISCUSSION: Given the high prevalence of malaria in Southern Ethiopia and Zambia, and the correlation between liver consumption and …

R-Α-Lipoic Acid And 4-Phenylbutyric Acid Have Distinct Hypolipidemic Mechanisms In Hepatic Cells, Bo He, Régis Moreau

Department of Nutrition and Health Sciences: Faculty Publications

The constitutive activation of the mechanistic target of rapamycin complex 1 (mTORC1) leads to the overproduction of apoB-containing triacylglycerol-rich lipoproteins in HepG2 cells. R-α-lipoic acid (LA) and 4-phenylbutyric acid (PBA) have hypolipidemic function but their mechanisms of action are not well understood. Here, we reported that LA and PBA regulate hepatocellular lipid metabolism via distinct mechanisms. The use of SQ22536, an inhibitor of adenylyl cyclase, revealed cAMP’s involvement in the upregulation of CPT1A expression by LA but not by PBA. LA decreased the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9) in the culture media of hepatic cells and increased …

Association Of Home Food Availability With Prediabetes And Diabetes Among Adults In The United States, Jennifer R. Mcatee, Meng-Hua Tao, Christian King, Weiwen Chai

Department of Nutrition and Health Sciences: Faculty Publications

This study examined associations of home food availabilities with prediabetes and diabetes among 8929 adults (20–70 years) participating in 2007–2010 National Health and Nutrition Examination Surveys. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were estimated by logistic regression. Relative to non-diabetic participants (individuals without diabetes or prediabetes), prediabetes participants were associated with lower availabilities of green vegetables (OR = 0.82; 95% CI = 0.73–0.91; p = 0.0006) and fat-free/low-fat milk (OR = 0.80, 95% CI = 0.65–0.89; p = 0.001) and higher sugary drink availability (OR = 1.24, 95% CI = 1.04–1.48; p = 0.02), adjusting for age, …

Application Of The Neuromuscular Fatigue Threshold Treadmill Test To Muscles Of The Quadriceps And Hamstrings, Clayton L. Camic, Attila J. Kovacs, Trisha A. Vandusseldorp, Ethan C. Hill Phd, Evan A. Enquist

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: The purposes of the present study were: (1) to determine whether the physical working capacity at the fatigue threshold (PWC_FT) model that has been used for estimating the onset of neuromuscular fatigue in the vastus lateralis (VL) during incremental treadmill running could also be applied to the vastus medialis (VM), biceps femoris (BF), and semitendinosus (ST) muscles; and (2) if applicable, to compare the running velocities associated with the PWC_FT among these muscles.

Methods: Eleven subjects (age 21.7 ± 1.8 years) performed an incremental treadmill test to exhaustion with electromyographic signals recorded from the …