Life Sciences Commons^™

Delta Tocotrienol Attenuates Nlrp3 Inflammasome Activation Via Inhibition Of Nf-Κb Priming And Reactive Oxygen Species Generation, Teresa Buckner

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Chronic, low-grade inflammation during obesity is associated with the development of metabolic dysfunction. The NLRP3 inflammasome is assembled in response to cellular stressors and leads to cytotoxic cytokines IL-1β and IL-18 production, which implicates the NLRP3 inflammasome in inflammatory conditions, including type 2 diabetes. Tocotrienols are antioxidant and anti-inflammatory forms of vitamin E. Delta-tocotrienol (dT3) displays NF-κB inhibitory and anti-oxidant abilities, and is easily isolated from the Annatto plant. My primary aim was to determine whether dT3 inhibits NLRP3 inflammasome activation and to compare the extent to which dT3 inhibits NLRP3 inflammasome with other tocotrienol forms, i.e. alpha-tocotrienol (aT3) and …

The Relationship Among Fifth Grade Physical Education Students' Body Size Perception, Fitnessgram Scores, And Physical Activity Level, Ashley N. Cleveland

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Purpose: This study aims to explore the correlation between students’ self-perception of body image and FITNESSGRAM scores, the relationship between children’s body perceptions and their actual body mass index (BMI), and to see if body image in children affects their physical activity level.

Methods: FITNESSGRAM fitness testing protocol and a survey developed for the KidQuest nutrition intervention program by South Dakota State University (SDSU) was used to assess the correlation between students’ (n= 319) self-perception of body image and FITNESSGRAM scores. In addition accelerometers were used to assess the physical activity level of a subsample (n=57) of the …