Life Sciences Commons^™

Nitrate, The Oral Microbiome, And Cardiovascular Health: A Systematic Literature Review Of Human And Animal Studies, Lauren C. Blekkenhorst, Nicola P. Bondonno, Alex H. Liu, Natalie C. Ward, Richard L. Prince, Joshua R. Lewis, Amanda Devine, Kevin D. Croft, Jonathan M. Hodgson, Catherine P. Bondonno

Research outputs 2014 to 2021

Background

Dietary nitrate is an important source of nitric oxide (NO), a molecule critical for cardiovascular health. Nitrate is sequentially reduced to NO through an enterosalivary nitrate-nitrite-NO pathway that involves the oral microbiome. This pathway is considered an important adjunct pathway to the classical l-arginine–NO synthase pathway.

Objective

The objective of this study was to systematically assess the evidence for dietary nitrate intake and improved cardiovascular health from both human and animal studies.

Design

A systematic literature search was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines by using key search terms in Medline and …

Strategies To Address The Complex Challenge Of Improving Regional And Remote Children’S Fruit And Vegetable Consumption, Stephanie L. Godrich, Christina R. Davies, Jill Darby, Amanda Devine

Research outputs 2014 to 2021

Fruit and vegetables (F&V) are imperative for good health, yet less than one per cent of Australian children consume these food groups in sufficient quantities. As guided by Social Cognitive Theory (SCT), this paper aimed to: (i) understand key informant perspectives of the amount, types and quality of F&V consumed by rural and remote Western Australian (WA) children; and, (ii) determine strategies that could increase F&V consumption among rural and remote WA children. This qualitative study included 20 semi-structured interviews with health, school/youth and food supply workers, focusing on topics including: quantity and type of F&V consumed and strategies to …

Vulnerable, Single And Living In Poverty: Women’S Challenges To Accessing Food In The Australian Capital Territory, Tanya Lawlis, Amanda Devine, Penney Upton

Research outputs 2014 to 2021

Objective: To explore challenges to food access faced by vulnerable women living in the Australian Capital Territory and surrounds.

Method: Qualitative study comprising semi‐structured interviews supplemented with quantitative demographic data.

Results:Forty‐one women, mean age of 43 years, living in government and community housing who had an income of

Conclusion: Access to safe, nutritious and healthy food is difficult for women living in poverty. Acknowledgement of challenges that contribute to women’s food insecurity by all stakeholders is essential to address the problem and build sustainable actions and solutions.

Implications for public health: Collaboration from all stakeholders within our food system …

Relationship Of Dietary Nitrate Intake From Vegetables With Cardiovascular Disease Mortality: A Prospective Study In A Cohort Of Older Australians, Alex H. Liu, Catherine P. Bondonno, Joanna Russell, Victoria M. Flood, Joshua R. Lewis, Kevin D. Croft, Richard J. Woodman, Wai H. Lim, Annette Kifley, Germaine Wong, Paul Mitchell, Jonathan M. Hodgson, Lauren C. Blekkenhorst

Research outputs 2014 to 2021

Purpose

Short-term trials indicate inorganic nitrate and nitrate-rich vegetables may have vascular health benefits. However, few observational studies have explored the relationship between nitrate intake and long-term cardiovascular disease (CVD) outcomes. The primary aim of this study was to investigate the association of nitrate intake from vegetables with CVD mortality in a sample of older Australians.

Methods

A subgroup of participants without diabetes or major CVD at baseline (1992–1994) were included from the Blue Mountains Eye Study, a population-based cohort study of men and women aged ≥ 49 years. Diets were evaluated using a validated food frequency questionnaire at baseline, …

Dietary Nitrate And Diet Quality: An Examination Of Changing Dietary Intakes Within A Representative Sample Of Australian Women, Jacklyn K. Jackson, Amanda J. Patterson, Lesley K. Macdonald-Wicks, Catherine P. Bondonno, Lauren C. Blekkenhorst, Natalie C. Ward, Jonathan M. Hodgson, Julie E. Byles, Mark A. Mcevoy

Research outputs 2014 to 2021

Dietary nitrate is increasingly linked to a variety of beneficial health outcomes. Our purpose was to estimate dietary nitrate consumption and identify key dietary changes which have occurred over time within a representative sample of Australian women. Women from the 1946–1951 cohort of the Australian Longitudinal Study on Women’s Health with complete food frequency questionnaire data for both 2001 and 2013 were included for analysis. Dietary nitrate intakes were calculated using key published nitrate databases. Diet quality scores including the Australian Recommended Food Score, the Mediterranean Diet Score and the Nutrient Rich Foods Index were calculated along with food group …