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Full-Text Articles in Life Sciences

Neural Bases Of Phonological And Semantic Processing In Early Childhood, Avantika Mathur, Douglas H. Schultz, Yingying Wang Dr. Jan 2020

Neural Bases Of Phonological And Semantic Processing In Early Childhood, Avantika Mathur, Douglas H. Schultz, Yingying Wang Dr.

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

During the early period of reading development, children gain phonological (letter-to-sound mapping) and semantic knowledge (storage and retrieval of word meaning). Their reading ability changes rapidly, accompanied by learning-induced brain plasticity as they learn to read. This study aims at identifying the neural bases of phonological and semantic processing in early childhood by using a combination of univariate and multivariate pattern analysis. Nineteen typically developing children between the age of five and seven performed visual word-level phonological (rhyming) and semantic (related meaning) judgment tasks during functional magnetic resonance imaging scans. Our multivariate analysis showed that young children with good reading …


Neural Systems For Reading Aloud: A Multiparametric Approach, W. Graves, Rutvik Desai, C. Humphries, M. Seidenberg, J. Binder Jun 2015

Neural Systems For Reading Aloud: A Multiparametric Approach, W. Graves, Rutvik Desai, C. Humphries, M. Seidenberg, J. Binder

Rutvik Desai

No abstract provided.


Neural Correlates Of Implicit And Explicit Combinatorial Semantic Processing, W. Graves, J. Binder, Rutvik Desai, L. Conant, M. Seidenberg Jun 2015

Neural Correlates Of Implicit And Explicit Combinatorial Semantic Processing, W. Graves, J. Binder, Rutvik Desai, L. Conant, M. Seidenberg

Rutvik Desai

No abstract provided.


Anatomy Is Strategy: Skilled Reading Differences Associated With Structural Connectivity Differences In The Reading Network, W. Graves, J. Binder, Rutvik Desai, C. Humphries, B. Stengel, M. Seidenberg Jun 2015

Anatomy Is Strategy: Skilled Reading Differences Associated With Structural Connectivity Differences In The Reading Network, W. Graves, J. Binder, Rutvik Desai, C. Humphries, B. Stengel, M. Seidenberg

Rutvik Desai

No abstract provided.


Where Is The Semantic System? A Critical Review And Meta-Analysis Of 120 Functional Neuroimaging Studies, J. Binder, Rutvik Desai, W. Graves, L. Conant Jun 2015

Where Is The Semantic System? A Critical Review And Meta-Analysis Of 120 Functional Neuroimaging Studies, J. Binder, Rutvik Desai, W. Graves, L. Conant

Rutvik Desai

No abstract provided.


A Piece Of The Action: Modulation Of Sensory-Motor Regions By Action Idioms And Metaphors, Rutvik Desai, L. Conant, J. Binder, H. Park, M. Seidenberg Jun 2015

A Piece Of The Action: Modulation Of Sensory-Motor Regions By Action Idioms And Metaphors, Rutvik Desai, L. Conant, J. Binder, H. Park, M. Seidenberg

Rutvik Desai

No abstract provided.


Network Dynamics Of Visual Naming, Christopher R. Conner Aug 2013

Network Dynamics Of Visual Naming, Christopher R. Conner

Dissertations & Theses (Open Access)

Recognition and naming of objects and actions are fundamental components of language. They involve several different systems working in coordination to accomplish a complex behavior. During visual naming, sensory and semantic processing are carried out by dedicated cortical substrates in the temporal and occipital lobes, while response selection and articulatory planning are handled by prefrontal cortex. Despite decades of research using lesion analysis, functional MRI and electro-encephalography, the precise dynamics involved remain unknown due to the inadequate spatio-temporal resolution of these methodologies. Of particular interest is the organization of semantic knowledge and the degree of serial and parallel organization of …


Aging Influences The Neural Correlates Of Lexical Decision But Not Automatic Semantic Priming, Brian T. Gold, Anders H. Andersen, Greg A. Jicha, Charles D. Smith Nov 2009

Aging Influences The Neural Correlates Of Lexical Decision But Not Automatic Semantic Priming, Brian T. Gold, Anders H. Andersen, Greg A. Jicha, Charles D. Smith

Neuroscience Faculty Publications

Human behavioral data indicate that older adults are slower to perform lexical decisions (LDs) than young adults but show similar reaction time gains when these decisions are primed semantically. The present study explored the functional neuroanatomic bases of these frequently observed behavioral findings. Young and older groups completed unprimed and primed LD tasks while functional magnetic resonance imaging (fMRI) was recorded, using a fully randomized trial design paralleling those used in behavioral research. Results from the unprimed task found that age-related slowing of LD was associated with decreased activation in perceptual extrastriate regions and increased activation in regions associated with …


Dissociation Of Automatic And Strategic Lexical-Semantics: Functional Magnetic Resonance Imaging Evidence For Differing Roles Of Multiple Frontotemporal Regions, Brian T. Gold, David A. Balota, Sara J. Jones, David K. Powell, Charles D. Smith, Anders H. Andersen Jun 2006

Dissociation Of Automatic And Strategic Lexical-Semantics: Functional Magnetic Resonance Imaging Evidence For Differing Roles Of Multiple Frontotemporal Regions, Brian T. Gold, David A. Balota, Sara J. Jones, David K. Powell, Charles D. Smith, Anders H. Andersen

Neuroscience Faculty Publications

Behavioral research has demonstrated three major components of the lexical-semantic processing system: automatic activation of semantic representations, strategic retrieval of semantic representations, and inhibition of competitors. However, these component processes are inherently conflated in explicit lexical-semantic decision tasks typically used in functional magnetic resonance imaging (fMRI) research. Here, we combine the logic of behavioral priming studies and the neurophysiological phenomenon of fMRI priming to dissociate the neural bases of automatic and strategic lexical-semantic processes across a series of three studies. A single lexical decision task was used in all studies, with stimulus onset asynchrony or linguistic relationship between prime and …