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Full-Text Articles in Life Sciences
Social Status Modulates Restraint- Induced Neural Activity In Brain Regions Controlling Stress Vulnerability , Sahba Seddighi, Matthew A. Cooper
Social Status Modulates Restraint- Induced Neural Activity In Brain Regions Controlling Stress Vulnerability , Sahba Seddighi, Matthew A. Cooper
Haslam Scholars Projects
Understanding the cellular mechanisms that control resistance and vulnerability to stress is an important step toward identifying novel targets for the prevention and treatment of stress-related mental illness. Dominant and subordinate animals have been shown to exhibit different behavioral and physiological responses to stress, with dominants often showing stress resistance and subordinates often showing stress vulnerability. We have previously found that dominant hamsters exhibit reduced social avoidance following social defeat stress compared to subordinate hamsters, although the extent to which stress resistance in dominants generalizes to non-social stressors is unknown. In this study, dominant, subordinate, and control male Syrian hamsters …
Environmental Effects On Drosophila Brain Development And Learning, Xia Wang, Amei Amei, J. Steven De Belle, Stephen P. Roberts
Environmental Effects On Drosophila Brain Development And Learning, Xia Wang, Amei Amei, J. Steven De Belle, Stephen P. Roberts
School of Medicine Faculty Publications
Brain development and behavior are sensitive to a variety of environmental influences including social interactions and physicochemical stressors. Sensory input in situ is a mosaic of both enrichment and stress, yet little is known about how multiple environmental factors interact to affect brain anatomical structures, circuits and cognitive function. In this study, we addressed these issues by testing the individual and combined effects of sub-adult thermal stress, larval density and early-adult living spatial enrichment on brain anatomy and olfactory associative learning in adult Drosophila melanogaster. In response to heat stress, the mushroom bodies (MBs) were the most volumetrically impaired among …
Early Life Immune And Physical Stress Directly Influences Anxiety-Like Behaviour In Adolescent Rats: Examining Sex Differences, Jordan M. Ward
Early Life Immune And Physical Stress Directly Influences Anxiety-Like Behaviour In Adolescent Rats: Examining Sex Differences, Jordan M. Ward
Electronic Thesis and Dissertation Repository
This thesis examined the effects of neonatal acute immune activation with the endotoxin, lipopolysaccharide (LPS) on postnatal days 3 and 5 on adolescent anxiety-like behaviour in rats before and after a stress period. Previous research has shown that adults rats exposed to LPS during the neonatal stage show anxiety-like behaviour following a period of stress. This thesis investigated this effect in adolescence. The present results showed significantly higher anxiety-like behaviour in saline controls, and a potential neuroprotective effect of low dose LPS (15 µg/kg) contrary to what was reported in adult rats. As well, a phase of stressful, aversive conditioning …
Role Of Exercise And Stress In Memory And Learning Of The Hippocampus, Paul Baker, Jeff Edwards
Role Of Exercise And Stress In Memory And Learning Of The Hippocampus, Paul Baker, Jeff Edwards
Journal of Undergraduate Research
Some of the most devastating diseases today are diseases of the mind. Common side effects of Alzheimer’s disease are dementia and memory loss and more than 44 million people suffer from the disease worldwide [1]. Other mental diseases such as Parkinson’s also have a dramatic impact on the memory and learning pathways. Understanding the mechanism involved with memory and learning will bring science that much closer to finding a permanent cure to these devastating diseases.
Mindfulness And Law Enforcement: An Effective Approach To Implementing Mindfulness For First Responders, Gina White
Mindfulness And Law Enforcement: An Effective Approach To Implementing Mindfulness For First Responders, Gina White
Mindfulness Studies Theses
An increasing number of studies show that people employed as first responders in high trauma service jobs tend to experience a high level of stress, at work and after hours. Studies suggest that constant exposure to job related stress leads to both physical and mental dysregulation. This study looks at the effects of implementing mindfulness tools and techniques to those working in law enforcement. Other works on this topic report mindfulness as a successful tool to increase wellbeing to a broad spectrum of populations. The methodology used in this study was designed specifically for first responders. The data findings were …
Central Role Of Vasotocin In The Neuroendocrine Regulation Of Stress Responses And Food Intake In Chickens, Gallus Gallus, Gurueswar Nagarajan
Central Role Of Vasotocin In The Neuroendocrine Regulation Of Stress Responses And Food Intake In Chickens, Gallus Gallus, Gurueswar Nagarajan
Graduate Theses and Dissertations
It is well known that arginine vasotocin (AVT) in birds is involved in physiological homeostasis such as cardiovascular, osmotic regulation as well as reproductive functions. Pertinent to these physiological functions, AVT immunoreactive (-ir) neurons in the hypothalamus have been found associated with hemorrhage, dehydration, oviposition and other physiological regulation. Evidence, however, suggests that AVT also plays significant roles in modulating behavior, memory, stress, and food intake. This dissertation research addresses the latter two neuroendocrine functions of AVT in detail within the chicken brain. First, the functional role of AVT-ir neurons in conjunction with corticotropin releasing hormone (CRH)-ir neurons in the …
The Psychophysiological Correlates Of Personality, Trauma, Posttraumatic Stress Disorder And Social Support, Meghan E. Pierce
The Psychophysiological Correlates Of Personality, Trauma, Posttraumatic Stress Disorder And Social Support, Meghan E. Pierce
UNLV Theses, Dissertations, Professional Papers, and Capstones
Theories considering the etiology of psychopathy suggest that trauma exposure, specifically childhood maltreatment and sexual abuse, is related to the development of callous-unemotional traits in children and adolescents, which are precursors to psychopathic traits in adulthood. Furthermore, posttraumatic stress disorder has an opposite relationship with many of the emotional and behavioral components of the two-factor model of psychopathy. Specifically, PTSD is positively associated to IA and traits associated with it and negatively associated with FD. Thus, this study sought to expand upon the current theories of a trauma-based etiology of psychopathy by investigating the relationship between trauma, PTSD, and psychopathic …
The Effect Of Ethanol Consumption And Stress On Brain Derived Neurotrophic Factor And Tropomyosin Receptor Kinase B Expression., Katie Marie Masters
The Effect Of Ethanol Consumption And Stress On Brain Derived Neurotrophic Factor And Tropomyosin Receptor Kinase B Expression., Katie Marie Masters
Chancellor’s Honors Program Projects
No abstract provided.
Expression Of Mammalian Dna In A Non-Native Cell System, Taylor Hyatt
Expression Of Mammalian Dna In A Non-Native Cell System, Taylor Hyatt
Undergraduate Honors Thesis Projects
In this study, we aimed to investigate the interaction between glucocorticoid receptors and calcium channels. To begin our research, we began to optimize the transfection efficiency of a glucocorticoid receptor within human embryonic kidney cells. Results found that this non-native cell was able to be transfected with pK7-GR-GFP DNA. Although it was unexpected, we were unable to obtain a transfection efficiency of 10% to move forward with other planned experiments. However, through our efforts, we were able to achieve a transfection efficiency of 0.04% and troubleshoot many difficulties that prevented obtaining a higher transfection efficiency. It was found that the …