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The Posterior Hypothalamus Exerts Opposing Effects On Nociception Via The A7 Catecholamine Cell Group In Rats, Y. Jeong, J. R. Moes, M. Wagner, J. E. Holden
The Posterior Hypothalamus Exerts Opposing Effects On Nociception Via The A7 Catecholamine Cell Group In Rats, Y. Jeong, J. R. Moes, M. Wagner, J. E. Holden
University Faculty Publications and Creative Works
Stimulation of the posterior hypothalamic area (PH) produces antinociception in rats and humans, but the precise mechanisms are unknown. The PH forms anatomical connections with the parabrachial area, which contains the pontine A7 catecholamine cell group, a group of spinally projecting noradrenergic neurons known to produce antinociception in the dorsal horn. The aim of the present study was to determine whether PH-induced antinociception is mediated in part through connections with the A7 cell group in female Sprague-Dawley rats, as measured by the tail flick and foot withdrawal latency. Stimulation of the PH with the cholinergic agonist carbachol (125nmol) produced antinociception …
The Posterior Hypothalamus Exerts Opposing Effects On Nociception Via The A7 Catecholamine Cell Group In Rats, Y. Jeong, J. R. Moes, M. Wagner, J. E. Holden
The Posterior Hypothalamus Exerts Opposing Effects On Nociception Via The A7 Catecholamine Cell Group In Rats, Y. Jeong, J. R. Moes, M. Wagner, J. E. Holden
University Faculty Publications and Creative Works
Stimulation of the posterior hypothalamic area (PH) produces antinociception in rats and humans, but the precise mechanisms are unknown. The PH forms anatomical connections with the parabrachial area, which contains the pontine A7 catecholamine cell group, a group of spinally projecting noradrenergic neurons known to produce antinociception in the dorsal horn. The aim of the present study was to determine whether PH-induced antinociception is mediated in part through connections with the A7 cell group in female Sprague-Dawley rats, as measured by the tail flick and foot withdrawal latency. Stimulation of the PH with the cholinergic agonist carbachol (125nmol) produced antinociception …
Pain As Fact And Heuristic: How Pain Neuroimaging Illuminates Moral Dimensions Of Law, Amanda C. Pustilnik
Pain As Fact And Heuristic: How Pain Neuroimaging Illuminates Moral Dimensions Of Law, Amanda C. Pustilnik
Faculty Scholarship
Legal statuses, prohibitions, and protections often turn on the presence and degree of physical pain. In legal domains ranging from tort to torture, pain and its degree do important definitional work by delimiting boundaries of lawfulness and of entitlements. The omnipresence of pain in law suggests that the law embodies an intuition about the ontological primacy of pain. Yet, for all the work done by pain as a term in legal texts and practice, it has had a confounding lack of external verifiability. As with other subjective states, we have been able to impute pain’s presence but have not been …