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Adhd Medication Is More Potent And Effective During Ovulation, Laurenf@Byu.Edu Ford
Adhd Medication Is More Potent And Effective During Ovulation, Laurenf@Byu.Edu Ford
Library/Life Sciences Undergraduate Poster Competition 2024
• Women escalate psychostimulant abuse more quickly than men. Women who are prescribed psychostimulants for ADHD report fluctuations in drug efficacy that correspond to their menstrual cycle.
• In rodents, females acquire psychostimulant addiction more readily and release more dopamine (DA) in the dorsal striatum, an effect mediated by estrogen.
• However, the impact of the estrous cycle in the nucleus accumbens (NAc), a core region for learning and addiction in the ventral striatum, is underexplored.
• Here, we examine cocaine, methylphenidate (Ritalin), and methamphetamine (Desoxyn) effects on DA transmission in male and naturally-cycling female mice.