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Full-Text Articles in Life Sciences
Preventing Alzheimer's: Effects Of Second Language Acquisition In Older Populations, Joshua Rhead
Preventing Alzheimer's: Effects Of Second Language Acquisition In Older Populations, Joshua Rhead
Undergraduate Honors Theses
Alzheimer’s disease continues to be a problem that medicine has few answers for. As a result, much research has been focused on finding a cure as well as interventions to help prevent the onset of the disease. One such intervention that has been proposed is to improve the brain’s efficiency and connectivity. A controversial method of achieving these results is through second language acquisition. Many provide evidence for or against the benefits of this intervention, but much remains unclear. Most of these studies focus on cognitive function and functional connectivity in language areas, but the default mode network, which is …
A Parametric Investigation Of Pattern Separation Processes In The Medial Temporal Lobe, Sarah E. Motley
A Parametric Investigation Of Pattern Separation Processes In The Medial Temporal Lobe, Sarah E. Motley
Theses and Dissertations
The hippocampus is thought to be involved in memory formation and consolidation, with computational models proposing the process of pattern separation as a means for encoding overlapping memories. Previous research has used semantically related targets and lures to investigate hippocampal responses to mnemonic interference. Here, we attempted to define the response function of the hippocampus and its inputs during pattern separation by parametrically varying target-lure similarity in a continuous recognition task. We also investigated the effect of task demands (intentional versus incidental encoding) on pattern separation processes. We collected functional magnetic resonance imaging (fMRI) data while participants were shown a …