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Neuroscience and Neurobiology

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Open Access Theses & Dissertations

2015

Chemoarchitecture

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Structural Organization Of The Connections Between Neurons Of The Paraventricular And Lateral Hypothalamic Regions In The Adult Male Rat, Berenise De Haro Jan 2015

Structural Organization Of The Connections Between Neurons Of The Paraventricular And Lateral Hypothalamic Regions In The Adult Male Rat, Berenise De Haro

Open Access Theses & Dissertations

The hypothalamus is a major integrator of homeostatic signals in the brain; within the hypothalamus, there are sub-regions with specific roles in regulating energy balance. For example, the lateral hypothalamic area (LHA) has been classically associated with feeding behaviors, and contains two major orexigenic cell populations expressing the neuropeptides melanin concentrating hormone (MCH) or hypocretin 1/orexin A (H/O). Similarly, the paraventricular nucleus of the hypothalamus (PVH) integrates information to mediate neuroendocrine and autonomic responses related to ingestive behaviors. The PVH has also been implicated directly in the control of feeding. However, the precise structural and functional interactions between these two …