Life Sciences Commons^™

Senile Dementia From Neuroscientific And Islamic Perspectives, Mohd Amzari Tumiran

Mohd Amzari Tumiran

Diseases involving the nervous system drastically change lives of victims and commonly increase dependency on others. This paper focuses on Senile Dementia (SD) from both the neuroscientific and Islamic perspectives, with special emphasis on the integration of ideas between the two different disciplines. This would enable effective implementation of strategies to address issues involving this disease across different cultures, especially among the world-wide Muslim communities. In addition, certain incongruence ideas on similar issues can be understood better. The former perspective is molded according to conventional modern science while the latter on the analysis of various texts including the holy Qur’an, …

Brain Activity And Medical Diagnosis: An Eeg Study, Laila M. Ribas, Fábio T. Rocha, Neli R. Ortega, Armando F. Rocha, Eduardo Massad

Armando F Rocha

Despite new brain imaging techniques that have improved the study of the underlying processes of human decision-making, to the best of our knowledge, there have been very few studies that have attempted to investigate brain activity during medical diagnostic processing.The main purpose of this paper was to investigate brain electroencephalography (EEG) activity associated with diagnostic decision-making in the realm of veterinary medicine using X-rays as a fundamental auxiliary test. The principal component analysis revealed four patterns that accounted for 85% of the total variance in the EEG activity recorded while veterinary doctors read a clinical history, examined an X-ray image …

Kisspeptin Receptor Agonist (Ftm080) Increased Plasma Concentrations Of Luteinizing Hormone In Anestrous Ewes, Brian K. Whitlock, Kelly A. Chameroy, Rebecca R. Payton, Shinya Oishi, Nobutaka Fujii, Joseph A. Daniel

Brian K Whitlock, PhD, DVM, DACT

Kisspeptin (KP) and the KP receptor (Kiss1r) are integral to central regulation of the gonadotropic-axis. The demonstration that intravenous infusion of KP can stimulate gonadotropin secretion and ovulation in seasonally anestrous female sheep offers a means of manipulating the reproductive axis. However, KP may be of limited clinical use because of the short circulating half-life. Kiss1r agonists with increased half-life and similar efficacy to KP in vitro potentially may provide beneficial applications in breeding management of many species. However, many of these agonists have not been tested in vivo. This study was designed to test and compare the effects of …

Effect Of Meloxicam On Gain And Inflammatory Response Of Calves Castrated By Banding Post-Weaning, Brian K. Whitlock, Peter D. Krawczel, Jeff A. Carroll, Nicole C. Burdick Sanchez, Jeff W. Dailey, Joseph A. Daniel, Johann F. Coetzee

Brian K Whitlock, PhD, DVM, DACT

Castration may detrimentally affect the health and performance of weaned calves, and painful procedures are increasingly becoming a public concern. The objective of this study was to determine the effects of castration (by banding) with or without administration of meloxicam, a non-steroid anti-inflammatory, on performance and inflammatory response in weaned beef calves. Forty-eight (weaned) beef calves [10.0±0.2 mo old; 304±6 kg BW] were blocked by age, BW, wither height, scrotal circumference, and source, then randomly assigned to 1 of 3 treatments (n=16 calves per treatment: 1) intact bulls (BULL), 2) castration by banding (BAN), or 3) castration by banding with …

Effect Of Meloxicam On Gain And Behavior Of Calves Castrated By Banding Pre-Weaning, Joseph A. Daniel, Peter D. Krawczel, Brian K. Whitlock

Brian K Whitlock, PhD, DVM, DACT

The objective was to determine if oral meloxicam (M; a non-steroid anti-inflammatory) administered at castration of pre-weaning calves affected ADG or behavior. Prior to castration (14 d), Angus bulls were assigned to bull (BULL; n = 7; age 106 ± 6 d; BW = 174.2 ±7.7 kg; scrotal circumference 17.7 ± 0.4 cm), castrated (BAN; n = 12; age = 105 ± 5 d; BW = 144.5 ± 7.6 kg; scrotal circumference = 16 ± 0.4 cm) or castrated with meloxicam (BAN+M; n = 13; age = 121 ± 6 d; BW = 145.8 ± 6 kg; scrotal circumference = …

Meloxicam Mediates Short-Term Behavioral Changes Of Castrated Calves, Peter D. Krawczel, Jeff A. Carroll, Nicole C. Burdick Sanchez, Jeff W. Dailey, Joseph A. Daniel, Johann F. Coetzee, Brian K. Whitlock

Brian K Whitlock, PhD, DVM, DACT

Castration may detrimentally affect the health and performance of weaned calves and painful procedures are increasingly a public concern. Therefore, practical pain mitigation is critical. The objective was to determine the effects of castration (by banding) with or without administration of NSAID, meloxicam, on the behavior of weaned beef calves. Forty-eight (56 d post-weaning) beef calves [10.0 ± 0.2 (mean ± SE) mo old; 304 ± 6 kg BW] were blocked by multiple factors then randomly assigned to 3 treatments (n = 16 calves per treatment: 1) intact bulls (BULL), 2) castration by banding (BAN), or 3) castration by banding …

Application Of Three-Dimensional Culture Conditions To Human Embryonic Stem Cell-Derived Definitive Endoderm Cells Enhances Hepatocyte Differentiation And Functionality, Thamil Selvee Ramasamy

Thamil Selvee Ramasamy

Human embryonic stemcells (hESCs) and induced pluripotent stemcells (iPSCs) provide an unlimited source for the generation of human hepatocytes, owing to their indefinite self-renewal and pluripotent properties. Both hESC-/iPSC-derived hepatocytes hold great promise in treating liver diseases as potential candidates for cell replacement therapies or as an in vitro platform to conduct newdrug trials. It has been previously demonstrated that the initiation of hESC differentiation in monolayer cultures increases the generation of definitive endoderm (DE) and subsequently of hepatocyte differentiation. However, monolayer culture may hinder the maturation of hESC-derived hepatocytes, since such two-dimensional (2D) conditions do not accurately reflect the …

What We Learn About Global Systemic Risk With Neurosciences, Armando F. Rocha

Armando F Rocha

Financial market crises are frequent events that trigger large financial losses and represent important global systemic risk (GSR). GSR forecasting is, therefore, a necessity to avoid the collapse of the global financial market. Understanding GSR dynamics is imperative if GSR is to be forecasted and controlled. Traditional finance theories have developed many tools for risk management that proved to be unreliable in the case of the 2008 Crisis. Recent results on financial decision-making provided by Neurosciences have being used to model the stock market dynamics. This approach is used, here, to model stock price evolution in 20 bourses during the …

A Neuromarketing Study Of Consumer Satisfaction, Armando F. Rocha, Fábio T. Rocha, Lucia H. Arruda

Armando F Rocha

The interest of marketing science in using neuroscience techniques to understand the consumer’s thought processes, dates back to the 1970s, when EEG data were recorded while subjects were watching TV commercials. Recently, fMRI was used to study the neural correlates of culturally based brands and neural predictors of purchases. These studies have discovered important properties of the neural circuits that are associated with consumer decision-making process and satisfaction. Here, EEG brain mapping was used to study the dynamics of the brain activity associated with these processes. The present study validated the EEG technology as an adequate neuromarketing tool and shows …

Gun Control: What Goes On In Your Brain, Armando F. Rocha, Fabio T. Rocha, Eduardo Massad

Armando F Rocha

Arguments for and against gun control are polarized at two opposite ends of a broad spectrum: personal liberties and social benefits. Brazil has introduced a referendum regarding the prohibition of firearm commerce and propaganda arguments, similar to the present ongoing discussion in the U.S. It has invoked socially and personally driven issues in the promotion of voting in favor of and against firearm control, respectively. Here, we used electroencephalography (EEG) technology to study the brain activity associated with a voter’s perception one week prior to Election Day, of the truthfulness of these arguments and their influence on voting decisions. The …

Brain Activity Follow Up Of Stock Market Financial Variables, Armando F. Rocha, João Vieito, Fábio T. Rocha

Armando F Rocha

Efficiency Market hypothesis assume that all investors reason in the same way to make their financial decisions. In contrast, Neurosciences have provided strong evidences that cognitive diversity is the hallmark of human intelligence. Neurofinances has shown that volunteers learned different profitable financial decision-making strategies depending on the kind of market they begun to trade. Here, we decide to further explore this hypothesis by studying a possible correlation between brain activity and the financial variables in a stock market game and to test if this correlation differ between experimental groups that trade in different market conditions. Present results show that volunteers …

Free Will From The Neuroscience Point Of View, Armando F. Rocha, Fábio T. Rocha

Armando F Rocha

There is still a controversy if human volitions and actions are governed by causal laws or obeys free will. Neurosciences start to study the neural correlates of free will by investigating how brains make decisions. Here, some of questions about free will are discussed from the neurosciences point of view taking into consideration a neuroeconomic model of decision making. This model is used here with the purpose of providing very formal definitions of key concepts raised in any free will discussion such as goals, necessity, motivation, etc., and to provide a formal background for discussing decision making. One of the …

Factors Influencing The Effectiveness Of Repellents In Managing Birds, Larry Clark

Larry Clark

No abstract provided.

Flatbed Scanner Report - Optical Density Dynamic Range, George Mcnamara

George McNamara

George McNamara (now at University of Miami) report for Hua Yu and Richard Jove, City of Hope National Medical Center, on optical density dynamic range of several flatbed scanners.

Introduction To Nanoscopy Nano-Talk, George Mcnamara

George McNamara

T7-1 is the designation for the LMRG Nanoscopy session at ABRF in Orlando, FL, on March 20, 2012. The PDF file here is a draft of my presentation.

May not be very helpful since (1) would probably help to know what is in my head and each slide will [hopefully] prompt me to say, and (2) 10 minute talk so I am going to push the "next slide" button after saying very little.

__________________

Publisher statement:

The T7-1 Introduction to Nanoscopy Nano Talk is copyrighted (c) George McNamara, 2012. Except for (1) screenshots from research articles (which are copyrighted by …

Rogers Pmn Movie - Background Information, George Mcnamara

George McNamara

Please see

http://mdc.custhelp.com/app/answers/detail/a_id/18689/~/metamatters-newsletters

for my series of MetaMorph MetaMatters articles in volume 2, numbers 3 through 6, on the Rogers PMN Panorama data set.

http://mdc.custhelp.com/app/answers/detail/a_id/18689/~/metamatters-newsletters

Brief summary (for more, see the Word doc)

Hslic Fall 2012 Scholarship Committee Report, Ann Jordan

Ann Jordan

No abstract provided.

The Evolved Apprentice. How Evolution Made Humans Unique, Mirko Farina

Mirko Farina

No abstract provided.

Perception, Action, And Consciousness: Sensorimotor Dynamics And Two Visual Systems, Mirko Farina

Mirko Farina

No abstract provided.

Do Ssds Extend The Conscious Mind?, Mirko Farina, Julian Kiverstein

Mirko Farina

Is the brain the biological substrate of consciousness? Most naturalistic philosophers of mind have supposed that the answer must obviously be «yes » to this question. However, a growing number of philosophers working in 4e (embodied, embedded, extended, enactive) cognitive science have begun to challenge this assumption, arguing instead that consciousness supervenes on the whole embodied animal in dynamic interaction with the environment. We call views that share this claim dynamic sensorimotor theories of consciousness (DSM). Clark (2009), a founder and leading proponent of the hypothesis of the extended mind, demurs, arguing that as matter of fact the biology of …

Mcnamara 2011 Mpmicro - Multi-Probe Microscopy (10/31/2011), George Mcnamara

George McNamara

Multi-Probe Microscopy is an ~1500 page Word document summarizing what I know and/or found interesting in light microscopy, fluorescence microscopy and digital image analysis, from 1995-2005. Very little has been updated since 2005.

Heifer Estrous Cycle Stage Impacts Luteinizing And Growth Hormone Response To Kisspeptin, Brian K. Whitlock, Joseph A. Daniel, Robyn R. Wilborn, Barbara P. Steele, James L. Sartin

Brian K Whitlock, PhD, DVM, DACT

The reproductive neuropeptide, kisspeptin (KP), may have a role in regulation of growth hormone (GH) secretion. Expression of KP and its receptor (Kiss1r) are developmentally and hormonally regulated. This study was conducted to determine the effects of KP on plasma concentrations of luteinizing hormone (LH) and GH in pubertal heifers during different functional reproductive stages. Heifers received a single injection of KP (100 pmole / kg) or saline intravenously during proestrus, estrus, and diestrus, and serial blood samples were collected for 3 hours to determine the response of both LH and GH after treatment. Mean concentrations of LH were increased …

Effect Of Kisspeptin On Regulation Of Growth Hormone, Brian K. Whitlock, Joseph A. Daniel, Robyn R. Wilborn, Herris S. Maxwell, Barbara P. Steele, James L. Sartin

Brian K Whitlock, PhD, DVM, DACT

Kisspeptin ( KP ), a neuroendocrine regulator of reproduction, is hypothesized to be an integrator of metabolism and hormones critical to the regulation of reproduction. Lactation is associated with enhanced growth hormone (GH) responsiveness and reduced fertility. Our study was designed to determine the effects of lactation on KP-stimulated GH and luteinizing hormone (LH) secretion. Five non-lactating and five lactating dairy cows were used in the study. Experiments were conducted with lactating cows at weeks 1, 5 and 11 after parturition. The experimental treatments ( saline and KP [100 and 400 pmol / kg body weight]) were given intravenously and …

The Effect Of Kisspeptin Receptor Agonist (Ftm080) On Luteinizing Hormone In Sheep, Brian K. Whitlock, Joseph A. Daniel, Maria Hes, Barbara P. Steele, James L. Sartin, S. Oishi, N. Fujii

Brian K Whitlock, PhD, DVM, DACT

Kisspeptin receptor (Kiss1r) agonists with increased half-life and similar efficacy to kisspeptin (KP) in vitro potentially may provide beneficial applications in breeding management of many species. However, many of these agonists have not been tested in vivo. This study was designed to test the effect of a Kiss1r agonist (FTM080) on luteinizing hormone (LH) in vivo. Sheep were treated with FTM080 (500 pmol/kg BW) or sterile water in a 2-ml bolus via the jugular cannula. Serial blood samples were collected every 15-min before (1 hr) and after (1 hr) treatment. Intravenous (IV) injection of FTM080 increased (P < 0.05) LH plasma concentrations through the 45-min sample following treatment. Moreover, the area under the curve of LH in the period from 0 to 60-min following FTM080 treatment was also increased (P < 0.05). These data provide evidence to suggest that FTM080 stimulates the gonadotropic axis of ruminants in vivo.

Embraining Culture: Leaky Minds And Spongy Brains, Julian Kiverstein, Mirko Farina

Mirko Farina

We offer an argument for the extended mind based on considerations from brain development. We argue that our brains develop to function in partnership with cognitive resources located in our external environments. Through our cultural upbringing we are trained to use artefacts in problem solving that become factored into the cognitive routines our brains support. Our brains literally grow to work in close partnership with resources we regularly and reliably interact with. We take this argument to be in line with complementarity or “second-wave” defences of the extended mind that stress the functional differences between biological elements and external, environmental …

The Brain As A Distributed Intelligent Processing System: An Eeg Study., Armando F. Rocha, Fábio T. Rocha, Eduardo Massad

Armando F Rocha

arious neuroimaging studies, both structural and functional, have provided support for the proposal that a distributed brain network is likely to be the neural basis of intelligence. The theory of Distributed Intelligent Processing Systems (DIPS), first developed in the field of Artificial Intelligence, was proposed to adequately model distributed neural intelligent processing. In addition, the neural efficiency hypothesis suggests that individuals with higher intelligence display more focused cortical activation during cognitive performance, resulting in lower total brain activation when compared with individuals who have lower intelligence. This may be understood as a property of the DIPS. In our study, a …

Cognitive Systems And The Extended Mind, Mirko Farina

Mirko Farina

No abstract provided.

The Faculty For Undergraduate Neuroscience: Learning Lessons Since 1991, Eric P. Wiertelak, Julio J. Ramirez, Jennifer R. Yates

Eric Wiertelak

No abstract provided.

Selected Hormonal And Neurotransmitter Mechanisms Regulating, James L. Sartin, Joseph A. Daniel, Brian K. Whitlock, Robyn R. Wilborn

Brian K Whitlock, PhD, DVM, DACT

Appetite control is a major issue in normal growth and in suboptimal growth performance settings. A number of hormones, in particular leptin, activate or inhibit orexigenic or anorexigenic neurotransmitters within the arcuate nucleus of the hypothalamus, where feed intake regulation is integrated. Examples of appetite regulatory neurotransmitters are the stimulatory neurotransmitters neuropeptide Y (NPY), agouti-related protein (AgRP), orexin and melanin-concentrating hormone and the inhibitory neurotransmitter, melanocyte-stimulating hormone (MSH). Examination of messenger RNA (using in situ hybridization and realtime PCR) and proteins (using immunohistochemistry) for these neurotransmitters in ruminants has indicated that physiological regulation occurs in response to fasting for several …

Supersizing The Mind: Embodiment, Action And Cognitive Extension, Mirko Farina

Mirko Farina

No abstract provided.