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The Effect Of Galactose On The Expression Of Genes Regulated By Rrp6p, Mary Megan Pelkowski, Kevin Callahan
The Effect Of Galactose On The Expression Of Genes Regulated By Rrp6p, Mary Megan Pelkowski, Kevin Callahan
The Review: A Journal of Undergraduate Student Research
Gene expression is a multi-faceted phenomenon, governed not only by the sequence of nucleotides, but also by the extent to which a particular gene gets transcribed, how the transcript is processed, and whether or not the transcript ever makes it out of the nucleus. Rrp6p is a 5’-3’ exonuclease that can function independently and as part of the nuclear exosome in Saccharomyces cerevisiae (Portin, 2014). It degrades various types of aberrant RNA species including small nuclear RNAs, small nucleolar RNAs, telomerase RNA, unspliced RNAs, and RNAs that have not been properly packaged for export (Butler & Mitchell, 2010). This exosome …