Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
Synergetic Effect Of Permethrin And Dmh On Anti-Oxidation And Damage Response Genes, Karim Mohamed
Synergetic Effect Of Permethrin And Dmh On Anti-Oxidation And Damage Response Genes, Karim Mohamed
Wayne State University Theses
The objective of this study was to evaluate the Synergetic Effect of Permethrin and 1,2-Dimethylhydrazine (DMH) on Anti-oxidation and Damage Response genes. The animal models used for this study were 8 week old C57/blk6 female mice. The mice were fed a Folate Adequate (FA) diet. At 8 weeks, the mice were intraperitoneally injected with pesticides. Three 8-week old female mice were injected intraperitoneally with a mix of cis and trans permethrin (75%:25% respectively) at 30% median lethal dose (96 mg/kg body weight). Permethrin was dissolved in corn oil and injected 24 hours before sacrifice. In three other mice, DMH was …