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Full-Text Articles in Life Sciences
Microbial Community Analysis: Biofilm Inhibition & Algae Associated Community Structure, Michelle V. Fong
Microbial Community Analysis: Biofilm Inhibition & Algae Associated Community Structure, Michelle V. Fong
University of the Pacific Theses and Dissertations
Natural products chemistry is the pursuit of bioactive small molecules from living organisms. These can be classified as primary metabolites if they are essential to survival, and secondary metabolites if they are accessory, playing a role in communication, defense, recruitment, etc.. Natural products have made a significant contribution to society – of 1,881 FDA-approved drugs from 1981 to 2019, 4% were pure natural products, 19% were natural products derived, and 3% were synthetic drugs with a natural products pharmacophore targeting a wide range of diseases and infections (Newman & Cragg, 2020). Pharmacophores are structural components of drugs that are responsible …
In Vitro Activity Of Four Fluoroquinolones On Selected Bacteria, Sheryl L. Pullen
In Vitro Activity Of Four Fluoroquinolones On Selected Bacteria, Sheryl L. Pullen
University of the Pacific Theses and Dissertations
In 1990-1991, in a national surveillance study, and in 1991-1992, in a followup study, both by Thornsberry et al. (1993), ciprofloxacin data from various geographical and demographical institutions were collected. Several species of bacteria have shown resistance to ciprofloxacin and norfloxacin, but the degree of resistance to these drugs has not been reported for the Stockton area. To determine the extent of this resistance, Dameron Hospital antibiograms generated from 1990 to 1994 were reviewed and compared. Results of the comparison show that susceptibility among the Gram-negative isolates, with the exception of Providencia stuartii, Acinetobacter lwoffi, and to a lesser extent …