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Microbiology

University of Wisconsin Milwaukee

Metabolism

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Cellular Metabolism And Its Effect On The Type Iii Secretion System Of Dickeya Dadantii 3937, William Cortrell Hutchins Aug 2013

Cellular Metabolism And Its Effect On The Type Iii Secretion System Of Dickeya Dadantii 3937, William Cortrell Hutchins

Theses and Dissertations

Nutrition, in both eukaryotes and prokaryotes, is vital to the life and well-being of the species. In organisms such as Escherichia coli, metabolism and its regulation have been well established, whereas in Dickeya dadantii 3937, the metabolic pathways and their effects on other processes have not been elucidated. Little is known is how carbon metabolism is able to regulate virulence and pathogenicity in this organism. In this work, we have investigated how the metabolic network contributes to positively and negatively regulating the pathogenicity of Dickeya dadantii 3937.

Chapter 1 provides an overview of the history and virulence processes in …