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Neutrophil Subtype Differentiation In Campylobacter Jejuni Infection And Its Impact On T Cells And Colonic Epithelial Cells, Carolina Dolislager
Neutrophil Subtype Differentiation In Campylobacter Jejuni Infection And Its Impact On T Cells And Colonic Epithelial Cells, Carolina Dolislager
Masters Theses
The discovery of neutrophil subtypes has expanded what is known about neutrophil functions, yet there is still much to learn about the role of these subtypes during bacterial infection. We investigated whether Campylobacter jejuniinduced differentiation of human neutrophils into the hypersegmented, CD16hi/CD62Llo[CD16hi/CD62Llo] subtype. In addition, we investigated whether C. jejuni-dependent differentiation of this neutrophil subtype induced cancer promoting activities ofhuman T cells and colonocytes, whichwere observed in other studies of hypersegmented, CD16hi/CD62Llo[CD16hi/CD62Llo] neutrophils. We found that C. jejunicauses a significant shift in human neutrophil populations to the hypersegmented, CD16 …
Ecological Controls On Successional Patterns In Bloom-Forming Cyanobacteria, Kyla L. Hooker
Ecological Controls On Successional Patterns In Bloom-Forming Cyanobacteria, Kyla L. Hooker
Masters Theses
Harmful algal blooms are widespread in lake ecosystems but the ecological factors underlying their formation and maintenance are poorly understood. We revisit classical ecological theories which characterize and evaluate contrasting bottom-up and top-down influences on the selection of phytoplankton groups, such as Microcystis aeruginosa. We begin with a data compilation and analysis of environmental data from Lake Erie. This data analysis of nutrient concentrations, pigment concentrations, and zooplankton biomasses helps us understand and interpret what is happening in the environment throughout the year. Thus, allowing us to build a mathematical model to test our hypothesis. Our mathematical model asses …