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Microbiology

SelectedWorks

Selected Works

2009

EPEC

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Full-Text Articles in Life Sciences

Effect Of Aqueous Extract Of Aegle Marmelos Fruit On Adherence And Β-Lactam Resistance Of Enteropathogenic Escherichia Coli By Down Regulating Outer Membrane Protein C, Murali Malliga Raman Jan 2009

Effect Of Aqueous Extract Of Aegle Marmelos Fruit On Adherence And Β-Lactam Resistance Of Enteropathogenic Escherichia Coli By Down Regulating Outer Membrane Protein C, Murali Malliga Raman

Murali Malliga Raman

Problem statement: Enteropathogenic Escherichia Coli (EPEC) continue to be a major health problem, leading to death due to diarrhea, predominantly in children below the age of five. Due to evolution of multi drug resistance in EPEC and side effects caused to host by antibiotics necessitated a search for alternative medicines from medicinal plants. One such medicinal plant used since ancient times to cure diarrhea is Aegle marmelos. This study was done to investigate the effect of aqueous extract of Aegle marmelos fruit (AEAM) on outer membrane protein C (OmpC) of EPEC, which plays a key role in adherence and antibiotic …