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Microbiology

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Jan A.C. Vriezen Dr.

2008

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Full-Text Articles in Life Sciences

The Role Of Sos Boxes In Enteric Bacteriocin Regulation, Jan A.C. Vriezen Dr., Osnat Gillor Dr., Margaret A. Riley Dr. Jan 2008

The Role Of Sos Boxes In Enteric Bacteriocin Regulation, Jan A.C. Vriezen Dr., Osnat Gillor Dr., Margaret A. Riley Dr.

Jan A.C. Vriezen Dr.

Bacteriocins are a large and functionally diverse family of toxins found in all major lineages of Bacteria. Colicins, those bacteriocins produced by Escherichia coli, serve as a model system for investigations of bacteriocin structure–function relationships, genetic organization, and their ecological role and evolutionary history. Colicin expression is often dependent on host regulatory pathways (such as the SOS system), is usually confined to times of stress, and results in death of the producing cells. This study investigates the role of the SOS system in mediating this unique form of toxin expression. A comparison of all the sequenced enteric bacteriocin promoters reveals …