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Microbiology

Grand Valley State University

Honors Projects

Microbiology

Publication Year

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

A Literature Review On Tumor Microenvironmental Immunosuppressive Mechanisms On Cd8+ T Lymphocytes That Contribute To Tumor Immune Evasion, Jessica R. Gabrysiak Apr 2021

A Literature Review On Tumor Microenvironmental Immunosuppressive Mechanisms On Cd8+ T Lymphocytes That Contribute To Tumor Immune Evasion, Jessica R. Gabrysiak

Honors Projects

The concept of tumor immune evasion is a prevalent obstacle in cancer research and the development of immunotherapies. Increased insight into mechanisms that are responsible for the escape of cancer cells from the immune system will help to improve therapeutic approaches and provide understanding into slowing disease progression by utilizing the body's immune system. With immunotherapy development on the forefront of cancer research due to seemingly attenuated toxicity and resistance when compared to traditional chemoradiotherapy, analyzing these obstacles is essential for emerging roles and future directions in the discipline of immuno-oncology. Understanding the immunosuppressive molecules that contribute to the process …


Senior Project: An Investigative Study Into The Bacterial Contamination Of Little Black Creek, Margaret I. Brenneman Apr 2020

Senior Project: An Investigative Study Into The Bacterial Contamination Of Little Black Creek, Margaret I. Brenneman

Honors Projects

An investigation of Escherichia coli concentrations in a west Michigan stream was conducted to determine sources of fecal contamination that impact water quality. Little Black Creek (LBC) is located in Muskegon County and discharges into Lake Michigan at the P.J. Hoffmaster Campground Beach. Often referred to as an “indicator bacteria,” water contaminated with E. coli has a high probability to contain other enteric pathogens as well. Beach water testing in 2020 using Colilert-18 methods revealed E. coli levels of 579 cfu/100mL in the creek discharge area that exceeded total body contact criteria of 300 cfu/100mL. A follow-up study of the …