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Full-Text Articles in Life Sciences
Distiphallus Morphology And Its Role In Copulation Dynamics In Anastrepha Suspensa (Loew), Taylor J. Inboden
Distiphallus Morphology And Its Role In Copulation Dynamics In Anastrepha Suspensa (Loew), Taylor J. Inboden
Masters Theses
Anastrepha suspensa (Diptera; Tephritidae) is an agricultural pest species
causing severe economic damage and is controlled, in part, by applying knowledge
of this species' reproduction (e.g., disrupting fertile copulations by SIT). During
copulation, males transfer sperm as well as protein rich fluids through an aedeagus
and distiphallus, which females then store in three spermathecae and one ventral
receptacle. Within the female reproductive tract, the ventral receptacle and the
three spermathecae are strategically separated from each other. I hypothesized
males' ability to direct sperm transfer within the female reproductive tract is
through the structures found in the distiphallus. Utilizing scanning electron …
Resolution Of The Nutritional Requirements And Metabolic Profile Of Clostridium Scindens Atcc 35704, A Major Bile Acid-Dehydroxylating Anaerobe In The Human Gut, Rachana Shrestha
Resolution Of The Nutritional Requirements And Metabolic Profile Of Clostridium Scindens Atcc 35704, A Major Bile Acid-Dehydroxylating Anaerobe In The Human Gut, Rachana Shrestha
Masters Theses
Bile acids (cholate and chenodeoxycholate) are synthesized from cholesterol in the human liver, and secreted in small intestine for food digestion. However, a portion of these primary bile acids is converted in the colon to toxic secondary bile acids, deoxycholate and lithocholate. Secondary bile acid formation is the result of 7α-dehydroxylating anaerobes, and one of the key players in this conversion is Clostridium scindens. Interestingly, little is known about the basic physiology and nutrition of C. scindens. Therefore, the goal of this research was to understand the nutritional requirement, and determine the 7α-dehydroxylation activity and end products from …
Biotransformation Of Oxo-Bile Acids Derivatives By Human Gut Bacteria, Laina Sallam
Biotransformation Of Oxo-Bile Acids Derivatives By Human Gut Bacteria, Laina Sallam
Masters Theses
Bile acids are one group of steroids that can be metabolically transformed by human gut anaerobes. One of these transformations is the conversion of primary bile acids to secondary bile acids by 7α-dehydroxylating gut bacteria such as Clostridium scindens, Clostridium hylemonae, and Clostridium hiranonis. These anaerobes metabolize bile acid derivatives via 3α- and 7α-hydroxysteroid dehydrogenases (HSDH). Studies to date have not reported if these organisms are capable of converting 12-oxolithocholic acid (12-oxoLCA) to deoxycholic acid (DCA). The emphasis of this study was to determine the ability of C. scindens ATCC 35704, C. hiranonis DSM 13275, and C. …