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Cross-Sectional Analysis Of Cortical Thickness Across The Lifespan, Thomas J. Hum-Hyder
Cross-Sectional Analysis Of Cortical Thickness Across The Lifespan, Thomas J. Hum-Hyder
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An understanding of the normal aging process across the lifespan is important for gaining an understanding the pathophysiological changes that occur in accelerated aging diseases, such as Alzheimer’s Disease Dementia (ADD) and Vascular Dementia (VaD). The present study cross-sectionally analyzed cortical thickness values derived from T1-weighted magnetic resonance images for two large cohorts: Human Connectome Project and the Mayo Clinic Study of Aging. The 897 participants aged between 22-36 from the Human Connectome Project and the 801 participants aged between 52-92 from the Mayo Clinic Study of Aging created a robust cohort of non-demented individuals across the lifespan. We found …