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Full-Text Articles in Life Sciences

Manganese Distribution Across The Blood-Brain Barrier. I. Evidence For Carrier-Mediated Influx Of Managanese Citrate As Well As Manganese And Manganese Transferrin, Janelle S. Crossgrove, David D. Allen, Bonny L. Bukaveckas, Susan S. Rhineheimer, Robert A. Yokel Jan 2003

Manganese Distribution Across The Blood-Brain Barrier. I. Evidence For Carrier-Mediated Influx Of Managanese Citrate As Well As Manganese And Manganese Transferrin, Janelle S. Crossgrove, David D. Allen, Bonny L. Bukaveckas, Susan S. Rhineheimer, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

Manganese (Mn) is an essential element and a neurotoxicant. Regulation of Mn movement across the blood–brain barrier (BBB) contributes to whether the brain Mn concentration is functional or toxic. In plasma, Mn associates with water, small molecular weight ligands and proteins. Mn speciation may influence the kinetics of its movement through the BBB. In the present work, the brain influx rates of 54Mn2+, 54Mn citrate and 54Mn transferrin (54Mn Tf) were determined using the in situ brain perfusion technique. The influx rates were compared to their predicted diffusion rates, which were determined from …


Cooking Attenuates The Ability Of High-Amylose Meals To Reduce Plasma Insulin Concentrations In Rats, Marc A. Brown, Leonard H. Storlien, Ian L. Brown, J Higgins Jan 2003

Cooking Attenuates The Ability Of High-Amylose Meals To Reduce Plasma Insulin Concentrations In Rats, Marc A. Brown, Leonard H. Storlien, Ian L. Brown, J Higgins

Faculty of Health and Behavioural Sciences - Papers (Archive)

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