Life Sciences Commons^™

Personalized Medicine: The Use Of Biomarkers And Molecularly Targeted Therapies For Patient Care And Cancer Intervention, Wafa Asad, Emily Schmitt Lavin

Mako: NSU Undergraduate Student Journal

Personalized medicine and targeted therapy have been emerging fields of study for the remediation and inhibition of cancer. Personalized medicine in the treatment of cancer involves using genetic, immune, and proteomic profiling to provide therapeutic options as well as prognostic background for every patient and their tumor’s genetic mutations. Targeted therapies allow researchers and medical personnel alike to determine the appropriate treatment for a patient based on the molecular basis and mechanistic actions of a cancerous tumor. The overall significance of this study was to express how these treatments use biomarkers to pinpoint the location, and severity of the cancer, …

A High Glucose Concentration Is Well Tolerated By Colorectal Adenocarcinoma And Melanoma Cells But Toxic To Normal Human Gingival Fibroblast: Results Of An In Vitro Investigation, Muhammad Alif Mazlan, Afzan Mat Yusof, Muhammad Lokman Md Isa

Makara Journal of Health Research

Background: Glucose is associated with weight gain, which increases the risk of cancer. There is insufficient information on the effects of high glucose concentrations on cell lines. This study evaluated the viability patterns of human cancer and normal cell lines treated with glucose.

Methods: Human gingival fibroblast (hGF), colorectal adenocarcinoma (HT29), and skin malignant melanoma (A375) cell lines were cultured and treated with additional glucose in three respective concentrations: 1 mg/ml, 5 mg/ml, and 10 mg/ml. Then, cell viability was measured using an MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide)-assay. The data were analyzed using the Statistical Package for the Social Sciences …

Lymphoma: Exploring Awareness In Lebanon, Nariman Salem, Lena Abou Merhi, Ghwia Adra, Rayan Ayoub, Nour El-Akash, Sara Chaar, Adeeb Awad Awad, Omar Dasuki,

BAU Journal - Health and Wellbeing

In 2012, 14.1 million patients were diagnosed with cancer worldwide of which 385,700 estimated new cases of non-Hodgkin lymphoma (NHL). Also, 81,080 new cases of lymphoma were reported in the United States (US) among both genders in 2016. In Lebanon, Lymphoma represents the fifth most frequent cancer, nonetheless, little is known regarding its epidemiological attributes. This study aims to determine the current knowledge of the Lebanese people living in Lebanon about Lymphoma. About 400 participants were approached in public places, universities, hospitals or work places in different regions across Lebanon. A survey including questions about lymph nodes, cancer and lymphoma …