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Full-Text Articles in Life Sciences
Association Of Vitamin D Deficiency With Hypertension In Uninsured Women, Sreenivasa R. Chandana, Lakshmi P. Kocharla, Susan S. Harris, Radhika R. Kakarala
Association Of Vitamin D Deficiency With Hypertension In Uninsured Women, Sreenivasa R. Chandana, Lakshmi P. Kocharla, Susan S. Harris, Radhika R. Kakarala
Journal of Health Disparities Research and Practice
Vitamin D deficiency is an epidemic in the United States. Uninsured women are at high risk due to a lower intake of vitamin D and limited sun exposure. We examined the association between vitamin D deficiency and hypertension in 96 uninsured women at a County Free Medical Clinic in urban Michigan. Questionnaires were used to obtain information about demographics, medical history including hypertension, and dietary habits. Measurements including blood pressure and serum 25(OH)D level were also collected. Prevalence of hypertension was higher in subjects with 25(OH)D less than 50nmol/l compared with others (85% vs. 27.3%, p = 0.014). For every …
The Effect Of Pentylenetetrazole-Induced Seizures On Blood-Brain Barrier Integrity In A Rat Model Of Preeclampsia, Mutlu Küçük, Mehmet Kaya, Nurcan Orhan, Oğuzhan Eki̇zoğlu, Erol Arslan, Nadi̇r Arican, Rabi̇a Candan Gürses, İmdat Elmas, Ri̇vaze Kalayci, Bülent Ahishali
The Effect Of Pentylenetetrazole-Induced Seizures On Blood-Brain Barrier Integrity In A Rat Model Of Preeclampsia, Mutlu Küçük, Mehmet Kaya, Nurcan Orhan, Oğuzhan Eki̇zoğlu, Erol Arslan, Nadi̇r Arican, Rabi̇a Candan Gürses, İmdat Elmas, Ri̇vaze Kalayci, Bülent Ahishali
Turkish Journal of Veterinary & Animal Sciences
The pathophysiological mechanisms underlying blood-brain barrier (BBB) disruption in preeclampsia/eclampsia have not been elucidated. This study investigated the effect of pentylenetetrazole (PTZ)-induced seizures on the functional and structural properties of the BBB during N (omega)-nitro-L-arginine methyl ester (L-NAME)-induced hypertension and proteinuria in pregnant rats. Animals were treated with L-NAME for 10 days, beginning on day 10 of pregnancy. The BBB permeability was determined by measurements of sodium fluorescein (NaFlu) extravasation into the brain. Occludin and aquaporin (AQP)-4 immunoreactivities were evaluated in brain sections. Severe proteinuria and significantly increased arterial blood pressure were observed following L-NAME treatment. PTZ-induced seizures in pregnant …