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Full-Text Articles in Life Sciences
The Effects Of 830nm Light On Inflammation In Retinitis Pigmentosa, Krystal Marie Bach
The Effects Of 830nm Light On Inflammation In Retinitis Pigmentosa, Krystal Marie Bach
Theses and Dissertations
Purpose: Retinitis Pigmentosa (RP) is an inherited retinal degenerative disease and the most common cause of blindness in developed countries, affecting approximately 1 in 4,000 people. RP is characterized by photoreceptor cell death and recent studies suggest that chronic inflammation may play a key role in the pathogenesis of RP. Currently, there are no known treatments or preventive measures to delay or halt the loss of photoreceptor cells. Photobiomodulation (PBM) by light in the far-red or near-infrared (NIR) range of the light spectrum has been documented to help promote cell survival and reduce inflammation in several disease states. Recent studies …
Effects Of 670 Nm And 830 Nm Light On The Immune Response To Borrelia Burgdorferi, Felice Chen
Effects Of 670 Nm And 830 Nm Light On The Immune Response To Borrelia Burgdorferi, Felice Chen
Theses and Dissertations
ABSTRACT
EFFECTS OF 670 NM AND 830 NM LIGHT ON THE IMMUNE RESPONSE TO BORRELIA BURGDORFERI
by
Felice Chen
The University of Wisconsin-Milwaukee, 2015
Under the Supervision of Dean T. Nardelli, Ph.D. and Janis T. Eells, Ph.D.
Lyme arthritis is a debilitating joint disorder that arises from Lyme disease, which is a result of infection by the spirochete Borrelia burgdorferi. Antibiotics are the traditional treatment for Lyme disease, but chronic arthritis may persist in some patients despite antibiotic treatment. Therefore, other forms of treatment for Lyme arthritis are needed. Photobiomodulation (PBM) using red or near-infrared light, with wavelengths between 630 …
Identification Of Immunomodulatory Cells Induced By 670 Nm Light Therapy In An Animal Model Of Multiple Sclerosis, Erin Christine Koester
Identification Of Immunomodulatory Cells Induced By 670 Nm Light Therapy In An Animal Model Of Multiple Sclerosis, Erin Christine Koester
Theses and Dissertations
Multiple sclerosis is an autoimmune, demyelinating disease characterized by neurodegeneration and inflammation of the central nervous system. It affects approximately 250,000 people in the United States alone, with women being affected two times more than men. Experimental Autoimmune Encephalomyelitis (EAE) is the primary animal model of MS, sharing clinical signs and histopathology with MS. The current paradigm supports MS/EAE induction by myelin reactive CD4+ T cells that cross the blood brain barrier to induce an inflammatory response that leads to the destruction of the myelin sheath and eventual loss of axons. Recent data suggest that axonal loss and disease progression …