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Articles 1 - 30 of 187
Full-Text Articles in Life Sciences
Toxicological Effects And Treatment Of Accidental Ingestion Of Simparica Trio® In Felis Catus: An Investigative Review, Aussia Stander
Toxicological Effects And Treatment Of Accidental Ingestion Of Simparica Trio® In Felis Catus: An Investigative Review, Aussia Stander
Honors Theses
Simparica TRIO®, a canine endectocide manufactured by Zoetis, contains sarolaner, moxidectin, and pyrantel pamoate salt in an orally administered chewable tablet. These compounds are all toxic to both cats and dogs in sufficient amounts. As Simparica TRIO® rises in popularity among pet owners, Felis catus (felines, cats) in multi-pet households (households with both cats and dogs) are at increased risk of overdosage and toxicosis from accidental ingestion of Simparica TRIO® due to their smaller weight.
Simparica TRIO® is not for feline use and little literature exists on the symptoms of and treatment for accidental ingestion …
Sarcopenia And The Importance Of Resistance Training And Protein-Rich Diets For Prevention Of Muscle Loss In Older Adults: A Literature Review And Informational Pamphlet, Madison Steele
Honors Theses
The growing prevalence of sarcopenia among older adults as well as youths has prompted further research aimed at developing effective preventative measures and treatment plans. Sarcopenia is often thought to occur solely due to aging, but several other factors contribute to progressive muscle loss. Previous research studies have found an effect of physical activity and dietary protein levels on the risk of developing sarcopenia as well as its onset age. This study aims to review existing knowledge in the field to compile an extensive list of sarcopenia causes and methods of prevention. The main causes identified in this review are …
The Use Of Vascular Endothelial Growth Factor In Ligament And Tendon Repair, Caroline O'Connell
The Use Of Vascular Endothelial Growth Factor In Ligament And Tendon Repair, Caroline O'Connell
Honors Theses
The studies in this review have shown that VEGF increases tensile strength, decreases inflammation, and increases vascularization. In studies using exogenous VEGF, it was found that VEGF increases collagen type III fibers, which increases biomechanical strength, and improves graft revascularization. From the research, it can be concluded that endogenous injection of VEGF is more beneficial than exogenous due to endogenous not causing laxity of the connective tissue. VEGF is beneficial when compared to normal post-operative results due to it decreasing the duration of symptoms and decreasing healing time. Using VEGF injection treatments, patients can return to pre-injury activity at a …
Acid Attack: How Escherichia Coli Strains Resist Acid Stress, Lindsey Miller
Acid Attack: How Escherichia Coli Strains Resist Acid Stress, Lindsey Miller
Honors Theses
The systems used by Escherichia coli to combat heightened levels of acidity within their environment are varied and complex. Four distinct systems used by E. coli to resist acid-induced stress were identified in 2004 by Foster (1), though six now are known today. These systems include the glucose-repressed, glutamate-dependent, arginine-dependent, lysine-dependent, ornithine-dependent, and serine-dependent acid resistance systems. Each system is also known by its corresponding abbreviation, AR1-AR6. What is known about each system varies due to identification date, complexity of the pathway, and amount of research completed. Within this paper, each system will be identified and the pathway defined, combining …
Monitoring The Leaching Of Bisphenol-A From Feminine Hygiene Products Using Fluorescence Spectroscopy, Madison Easley
Monitoring The Leaching Of Bisphenol-A From Feminine Hygiene Products Using Fluorescence Spectroscopy, Madison Easley
Honors Theses
Bisphenol-A (BPA) is a compound commonly used as a stabilizer in plastic products, including food storage containers and thermal paper receipts. Because BPA can bind to and activate estrogen receptors, it is linked to reduced fertility, altered development, and hormone-related cancers. A recent study at NYU Medical School confirmed the presence of BPA in pantyliners, pads, tampons, feminine washes and deodorants. This is concerning due to the high absorption capacity of the vulvar skin.
For the research performed in our lab this summer, the goal was to determine if fluorescence spectrophotometry could be used to determine the presence of BPA …
Sleep Duration Is Associated With Caudate Volume And Executive Function, Nicole Jones
Sleep Duration Is Associated With Caudate Volume And Executive Function, Nicole Jones
Honors Theses
The ineligible role of the caudate nucleus in sleep has been implicated throughout multiple scientific studies. Previous literature has shown that greater caudate volume is associated with longer habitual sleep duration in older adults- ranging from 55 years of age and up. However, the association between sleep duration and caudate volume remains unknown in the younger population. In this study, we examined the caudate volume in youth to older adults (10 to 85 years old) with a greater sample size (N=464) to increase statistical power. The volumetric size of the caudate nucleus showed significantly positive association with habitual sleep duration, …
Comparing Calculated And Perceived Energy Needs In Collegiate Student-Athletes, Lyndsey T. Reed
Comparing Calculated And Perceived Energy Needs In Collegiate Student-Athletes, Lyndsey T. Reed
Honors Theses
The purpose of this study was to evaluate NCAA student-athletes' level of knowledge related to their energy needs. The participants were 75—42 male and 33 female—NCAA Division I student-athletes enrolled at the University of Mississippi (UM) from a variety of sports. In-person data collection took place at UM Athletics facilities by sports registered dietitians during team talks. The names of the athletes were used to find their pre-existing calculated energy, resting metabolic rate (RMR) and total energy expenditure (TEE) using the Nelson equation and the appropriate activity factor. Questionnaire and RMR/TEE data were analyzed and compared to assess knowledge related …
Education Opportunities For The Aspiring Aquatic Professional: A Qualitative Analysis Of Experience-Based Building Blocks For Success, Hannah Hickman
Education Opportunities For The Aspiring Aquatic Professional: A Qualitative Analysis Of Experience-Based Building Blocks For Success, Hannah Hickman
Honors Theses
While recent growth in the aquatics industry requires professionals to be more skilled and knowledgeable than ever before, educational opportunities for students pursuing this career are limited. There is not an all-encompassing course or degree program titled, "How to be an Aquatic Professional." This study utilizes interviews from 10 aquatic professionals regarding their experiences and opinions on this topic to explore the need for promoting aquatics education to students and to help outline a series of building blocks that students could potentially take to pursue a career as an aquatic professional. It attempts to answer the question: How do educational …
The Effects Of Light Intensity And Cell Structure On The Cultivation Of Arthrospira Platensis, Taylor Barnhart
The Effects Of Light Intensity And Cell Structure On The Cultivation Of Arthrospira Platensis, Taylor Barnhart
Honors Theses
As scientists explore further into space, more cost-effective resources are needed for long-term space travel. An interesting solution is Arthrospira platensis, a filamentous cyanobacteria high in proteins and nutrients, and known for its helical structure. In unfavorable conditions, coiled spirulina cells become straight. Spirulina converts carbon dioxide gas into pure oxygen and the different cell structures stimulate different responses in oxygen production and cultivation. In these experiments, 2.3 L containers of pure coiled spirulina and mixed (coiled and straight) spirulina were placed into 3 incubators with different light intensities: 51μmol/m2/s, 25μmol/m2/s, 12μmol/m2/s. Each experiment length was 72 hours and the …
A Review Of How Bioinformatics And Genome Sequencing Are Affecting Precision Medicine, Taylor S. Hickey
A Review Of How Bioinformatics And Genome Sequencing Are Affecting Precision Medicine, Taylor S. Hickey
Honors Theses
Advancement in genomic sequencing and bioinformatics methods have been affecting biomedical research through precision medicine, especially in the area of cancer. Vaccine therapies can be developed using neoantigens that target specific mutations in tumors. The goals of this research are to identify mutations that lead to cancer and then define subpopulations in which patients can easily be identified. The future goal is to have targeted vaccines that are specific to each subpopulation ready to be used in treatment of their cancer. Limitations to reaching these goals have been due to tumor heterogeneity, cancer location, and difficulty in creating neoantigens for …
Education, Beliefs, And Health Literacy Of Care Providers On Mouth Care Of Older Adults, Molly Lakin
Education, Beliefs, And Health Literacy Of Care Providers On Mouth Care Of Older Adults, Molly Lakin
Honors Theses
Oral health is important to one’s overall health and quality of life as it can lead to chronic illnesses such as cardiovascular disease, stroke, and neurodegenerative disorders (Haumschild et al. 2021). In long-term care facilities, it is important that dependent older adults are provided mouth care to maintain their oral health and decrease their chances of developing a chronic illness; however, there are barriers affecting the level, quality, and quantity of mouth care being provided in these facilities. A survey was developed to look at the education, beliefs, and health literacy of care providers on providing mouth care in hopes …
Importance Of Pelvic Floor Education And Rehabilitation Techniques For Adolescents And Young Adults: A Review, Katherine Laura Schmidt
Importance Of Pelvic Floor Education And Rehabilitation Techniques For Adolescents And Young Adults: A Review, Katherine Laura Schmidt
Honors Theses
The pelvic floor is the collection of many muscles forming what is often called the pelvic girdle. Understanding the different muscles and their roles is an important part of pelvic floor education. Although both males and females have pelvic floors, there is a lack of knowledge of basic anatomy seen in adolescents and young adults. This review analyzes the importance of providing more education for students about the pelvic floor, gives examples of common pelvic disorders for young adults, and provides details on the physical therapy rehabilitation techniques offered today to treat these conditions.
Antimicrobial Resistance In Eskape Pathogens And Its Effect On Modern Medicine And Treatment, Cameran Runge
Antimicrobial Resistance In Eskape Pathogens And Its Effect On Modern Medicine And Treatment, Cameran Runge
Honors Theses
Abstract
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter
spp.) are seeing a growing resistance to multiple classes of antibiotics. Misuse and overuse of antibiotics have played directly into the resistance observed, and the problem is growing exponentially. Antibiotic resistance is partially due to several intrinsic factors limiting the drug's uptake. These include efflux pumps, increased biofilm production, and reduced cell wall permeability in the resistant bacteria. ESKAPE pathogens also acquire resistance through horizontal gene transfer and plasmids. As antibiotics have become less effective, the bacteria can continue to thrive, leading to a detrimental …
Anti-Microbial Peptide Screen For Crop Protection, Sydney Chen
Anti-Microbial Peptide Screen For Crop Protection, Sydney Chen
Honors Theses
Vestaron currently uses an established and reliable peptide discovery and development research platform, particularly for the development of insecticidal peptides. The platform centers around a proprietary yeast expression system for peptide production (“Vestaron’s yeast expression system"). Vestaron aims to expand their portfolio and provide clean solutions in crop protection using peptide technologies to protect plants not only from insect pests but also microbial pests including phytopathogenic fungi and bacteria. Antimicrobial peptides (AMPs) have been studied extensively. However, it is questionable whether Vestaron’s yeast expression system can express AMPs heterologously. In this study, thirteen promising antimicrobial peptides were selected from literature …
Literature Replication: Insect Gut Cell Isolation Protocols, Sophie Pickelner
Literature Replication: Insect Gut Cell Isolation Protocols, Sophie Pickelner
Honors Theses
A large problem in science is the lack of literature replication, especially for subjects in which there is little published research. Literature replication is an integral part of the scientific method and is important for validating methods and results of published studies. A study from Nature found that out of 1,500 scientists interviewed, over 70% have been unable to reproduce literature studies and over half of them have been unable to reproduce even their own studies (Baker, 2016). This problem is even more pronounced in the field of biology, with 80% of scientists reporting that they are unable to replicate …
Effects Of Cannabichromene On Pain And Neuroinflammation In Hiv-1 Tat Transgenic Mice, Sydney Wheeler
Effects Of Cannabichromene On Pain And Neuroinflammation In Hiv-1 Tat Transgenic Mice, Sydney Wheeler
Honors Theses
HIV-1 TransActivator of Transcription (Tat) is a vital regulatory protein involved in HIV replication and implicated in development of HIV-associated pain and neurocognitive deficits. Tat is thought to contribute to these pathologies through proinflammatory pathways. Developing mechanisms to curb Tat-mediated inflammation is a key step in improving the quality of life of those living with HIV. Both recreational and medicinal cannabis use is prevalent among many people living with HIV; given this prevalence and the perceived anti-inflammatory benefits of cannabis use, it is important to investigate how chemical constituents of cannabis may impact HIV. In the present study, the effects …
The Effects Of Exercise On Adults With Intellectual And Developmental Disabilities, Addison Bates
The Effects Of Exercise On Adults With Intellectual And Developmental Disabilities, Addison Bates
Honors Theses
Exercise is essential for a healthy life and many people are unable to participate due to barriers. One population that seems to be extremely impacted by these barriers are persons with disabilities. People with disabilities are more likely to become obese and suffer from serious, chronic illnesses. There is a need for exercise programs catered to this population. There is a lack of exercise programs focused on people with disabilities, so through this research we are interested to see the impact of a 12-week exercise program and what results might occur from this lifestyle change. With the 12-week virtual program …
Inhibiting Effects Of Methyllycaconitine (Mla) On Pnu-282987 Induced Neurogenesis In Blast-Exposed Mouse Retinas, Nastia Zhiyew Chan
Inhibiting Effects Of Methyllycaconitine (Mla) On Pnu-282987 Induced Neurogenesis In Blast-Exposed Mouse Retinas, Nastia Zhiyew Chan
Honors Theses
Irreversible vision loss can be caused by retinal damage, disease, or aging. In recent years, the prevalence of ocular damage due to blast trauma has been increasing due to the modernization of warfare. Adult mammalian retinal neurons were previously thought to lack the capacity for regeneration to reverse vision loss, which deemed the effects of many ocular damages permanent. However, recent studies from this lab have shown that PNU-282987, an agonist to the alpha 7 subtype of neural nicotinic acetylcholine receptors, will result in neural regeneration in adult mammalian cells. For this research project, I will be using Methyllycaconitine (MLA), …
Exploring Modern Trends And Prevention Strategies For Childhood Obesity: A Comprehensive Literature Review, Anya E. Bogen
Exploring Modern Trends And Prevention Strategies For Childhood Obesity: A Comprehensive Literature Review, Anya E. Bogen
Honors Theses
This literature review seeks to provide an overview of the current research on childhood obesity. The study examines the prevalence and causes of childhood obesity, including genetic, environmental, and behavioral factors. The review also discusses the health consequences associated with childhood obesity, such as the increased risk for chronic diseases and psychological and social problems. Additionally, the review explores the effectiveness of interventions designed to prevent childhood obesity, including individual lifestyle modifications, education from health practitioners and school programs, and global, national, and state programs to promote wellness. The literature review concludes that childhood obesity is a complex and multifactorial …
A Look Into The Physiological Impacts Of Childhood Cancers And Modeling Of Tumor Growth Rate, Erica Steiner, Kimberly Hansen, Marissa Stanton
A Look Into The Physiological Impacts Of Childhood Cancers And Modeling Of Tumor Growth Rate, Erica Steiner, Kimberly Hansen, Marissa Stanton
Honors Theses
Cancer is one of the deadliest diseases present in the world. Children have different reactions to diseases and treatments; thus, it is important to study those reactions specifically in children. Knowing how children are impacted by these factors can be helpful in diagnosis and treatment of cancer. I performed this study by researching the different types of cancer I was interested in and using MATLAB to code for and simulate a growth curve of a brain tumor. I found that there are many different physiological impacts of different cancers in children. As for the modeling, I was able to get …
College Students' Relationship With Attention Deficit Hyperactivity Disorder And Learning Accommodations At The University Of Nebraska-Lincoln, Brianna Danehey, Kim Hansen Dr., Chelsea Witt Dr.
College Students' Relationship With Attention Deficit Hyperactivity Disorder And Learning Accommodations At The University Of Nebraska-Lincoln, Brianna Danehey, Kim Hansen Dr., Chelsea Witt Dr.
Honors Theses
Attention deficit hyperactivity disorder (ADHD) can provide many challenges for college students due to difficulties focusing, multi-tasking, and staying organized. Colleges are required to offer academic accommodations to students with disabilities in an attempt to provide students with an equitable learning environment. However, accommodations may be ineffective if they are highly unattainable, unused by the student once granted, or hindered by university faculty.
The objective of this study was to identify barriers to receiving effective and beneficial academic accommodations for individuals with ADHD at the University level and to provide insight into college students' knowledge and relationships relating to the …
The Effects Of Temperature And Mito-Nuclear Interaction On Male Fertility In Drosophila., Violetta Bakunina
The Effects Of Temperature And Mito-Nuclear Interaction On Male Fertility In Drosophila., Violetta Bakunina
Honors Theses
The (simw501);Ore genotype is a strain of Drosophila melanogaster that has impaired mitochondrial function as a result of a disrupted interaction between a mitochondrially-encoded tRNATyr and the nuclear-encoded synthetase that aminoacylates mt-tRNATyr. We hypothesized that disruption of mitochondrial protein synthesis and oxidative phosphorylation (OXPHOS) in this genotype decreases mitochondrial translation and results in the sterility of (simw501);OreR males at 28oC. The results of Mitotracker staining showcased the reduced Mean Fluorescence Intensity (MFI), which confirms that sterility has an energetic basis, yet also that mature sperm function is compromised. Cytological dissection of male gonads …
Syndemics And Social Factors: Infectious Disease Patterns Within The Population Of People Experiencing Homelessness In The United States, Kathleen Berzonsky
Syndemics And Social Factors: Infectious Disease Patterns Within The Population Of People Experiencing Homelessness In The United States, Kathleen Berzonsky
Honors Theses
Individuals experiencing homelessness are at increased risk of suffering from infectious diseases. This is due to a number of social factors and healthcare disparities, as well as the idea of syndemics, by which diseases cluster together to worsen disease burden. Current intervention strategies approach treatment from a post-infection perspective, but reducing transmission rates of infectious diseases within the population of people experiencing homelessness will require a shift in the healthcare framework. The issue of people experiencing homelessness must be viewed through a biosocial lens, focusing on preventative care and treatment. I provide an overview of the social factors governing infectious …
Advertising Sports Nutrition Practices To Adolescent Athletes: A Poster Series, Emma Hansen
Advertising Sports Nutrition Practices To Adolescent Athletes: A Poster Series, Emma Hansen
Honors Theses
Sports nutrition is an important aspect of an athlete’s training and improvement, yet it is often overlooked when it comes to younger competitors. Four posters were created with the intent of providing adolescent athletes, their parents, and their coaches with information about important topics in sports nutrition including a general overview of nutrition goals, hydration strategies, recovery nutrition, and nutritional considerations for vegetarian and vegan youth athletes. The posters were designed to appeal to adolescents from the ages of 13 to 18, and each poster covers its designated topic in detail appropriate for middle and high school-aged athletes. The accompanying …
Encouraging Or Guilt-Inducing? An Analysis Of Fitspiration Content And Its Effect On Body Image And Lifestyle Changes, Brenna Mazour
Encouraging Or Guilt-Inducing? An Analysis Of Fitspiration Content And Its Effect On Body Image And Lifestyle Changes, Brenna Mazour
Honors Theses
More people are acquiring their nutrition and exercise information from social media accounts called fitspiration. Analyses of fitspiration content have found the focus to be on restrictive diets and excessive exercise that’s appearance driven. Although its intent is to inspire its consumers to change their lifestyle, many speculate that it brings upon negative body image and induces guilt. The Theory of Planned Behavior (TPB) has been used to determine why people take part in certain health behaviors, such as diets or exercise regimens posted on fitspiration. TPB shows how the characteristics of social media discourage people to use fitspiration as …
“Exploring The Advantages And Disadvantages Of Universal Electronic Medical Records”, Zachary Mcclenny
“Exploring The Advantages And Disadvantages Of Universal Electronic Medical Records”, Zachary Mcclenny
Honors Theses
A universal electronic medical record (EMR) is a platform where all of a patient's medical information, history, and data is stored and maintained by providers over time. A universal platform allows all of the medications, tests, procedures, labs, scans, notes, and any other clinical information for that patient to be kept in a record for any provider to view and make changes to while under their care. Although in the United States today, as well as many other countries, EMRs are owned and operated by privately ran businesses and institutions. Only the private institutions that have access to the EMR …
Sex-Specific Effects Of High-Fat And Ketogenic Diet On Inflammatory Responses In The Hippocampus, Shalet James
Sex-Specific Effects Of High-Fat And Ketogenic Diet On Inflammatory Responses In The Hippocampus, Shalet James
Honors Theses
Poor diet and metabolic diseases (obesity, Type 2 diabetes) are associated with increased risk of neurodegenerative and neuropsychiatric disorders, including Alzheimer’s disease, anxiety, and depression. Studies indicate that inflammation in the hippocampus could be one mechanism linking these conditions. Previous findings on inflammation, specifically glial activity in response to a high-fat diet, indicate sex differences in microglial responses in the hippocampus. The ketogenic diet is characterized by a high-fat, low-carbohydrate, and moderate-protein diet. While the ketogenic diet is very high in fat content, it may also possess neuroprotective properties against brain aging and neurodegenerative disorders, as well as boost mood …
Effects Of Red Light Intensity On Cultivation And Oxygen Production In Arthrospira Platensis, Abigail Roberts
Effects Of Red Light Intensity On Cultivation And Oxygen Production In Arthrospira Platensis, Abigail Roberts
Honors Theses
Maintaining life sustaining resources during long-term space travel has encouraged scientists to turn their attention to the potential benefits of a cyanobacteria named Arthrospira platensis, commonly known as Spirulina algae. This experiment measures the oxygen production and cell population growth of two structurally different Spirulina cultures under two different levels of red light intensities, 8 µmol/m2/s (high); 3 µmol/m2/s (low). The cell population, oxygen produced, and oxygen produced per cell measurements were observed and recorded at three 24 hour intervals. It was found there was not a significant difference between high and low light intensities when considering the cell concentration …
Effects Of Red Light Intensity On Cultivation & Oxygen Production In Arthrospira Plantensis, Abigail Roberts
Effects Of Red Light Intensity On Cultivation & Oxygen Production In Arthrospira Plantensis, Abigail Roberts
Honors Theses
Maintaining life sustaining resources during long-term space travel has encouraged scientists to turn their attention to the potential benefits of a cyanobacteria named Arthrospira platensis, commonly known as Spirulina algae. This experiment measures the oxygen production and cell population growth of two structurally different Spirulina cultures under two different levels of red light intensities, 8 µmol/m 2Js (high); 3 µmol/m2/s (low). The cell population, oxygen produced, and oxygen produced per cell measurements were observed and recorded at three 24 hour intervals. It was found there was not a significant difference between high and low light intensities when considering the cell …
A Survey Of Speech-Language Pathologists' Academic Preparation In Craniofacial Anomalies, Francesca Myerski
A Survey Of Speech-Language Pathologists' Academic Preparation In Craniofacial Anomalies, Francesca Myerski
Honors Theses
Craniofacial anomalies occur in 1 of 750 newborns a year with the three main types being cleft lip, cleft palate, and cleft lip and/or cleft palate. There are six main factors that affect craniofacial anomalies that are focused on in this research, including genetics, environmental factors, medications, diet, health risks, and surgical procedures/surgeons. The research found that there is a lot of information on craniofacial anomalies and speech-language pathologists need to learn about as much as possible. The lack of knowledge and academic preparations speech-language pathologists have in craniofacial anomalies has decreased their awareness in the birth defect and has …