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An Immunohistochemical Study Of Her2 Expression In Primary Brain Tumors, Mazaher Ramezani, Shadi Siami, Mansour Rezaei, Sedigheh Khazaei, Masoud Sadeghi
An Immunohistochemical Study Of Her2 Expression In Primary Brain Tumors, Mazaher Ramezani, Shadi Siami, Mansour Rezaei, Sedigheh Khazaei, Masoud Sadeghi
BioMedicine
Background: Primary brain tumors (PBTs) include any tumor in the brain whose prognosis is weak because of their histological characteristics. Aim: Herein, this study aimed to assess the HER2 tumor marker frequency in PBTs. Materials and methods: This study was done on the samples of primary brain tumor diagnosis from 2008 to 2015. Results: Out of 107 patients of brain tumor that had a mean age of 40.4 years (61.7% men), the most common location of the tumor was in the supratentorial region (63.85% cases). The prevalence of high-grade astrocytoma (HGA) and low-grade astrocytoma (LGA) at diagnosis was 43.9% …