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A Method For Independent Component Graph Analysis Of Resting-State Fmri, Demetrius Ribeiro De Paula, Erik Ziegler, Pubuditha M. Abeyasinghe, Tushar K. Das

Anatomy and Cell Biology Publications

Introduction: Independent component analysis (ICA) has been extensively used for reducing task-free BOLD fMRI recordings into spatial maps and their associated time-courses. The spatially identified independent components can be considered as intrinsic connectivity networks (ICNs) of non-contiguous regions. To date, the spatial patterns of the networks have been analyzed with techniques developed for volumetric data. Objective: Here, we detail a graph building technique that allows these ICNs to be analyzed with graph theory. Methods: First, ICA was performed at the single-subject level in 15 healthy volunteers using a 3T MRI scanner. The identification of nine networks was performed by a …