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Full-Text Articles in Life Sciences
Tanapox: A Potential Oncolytic Virus For The Treatment Of Cancer, Joel Marty
Tanapox: A Potential Oncolytic Virus For The Treatment Of Cancer, Joel Marty
Honors Theses
The National Cancer Institute defines cancer as a group of related diseases characterized by unimpeded cell division with metastatic abilities. Cells frequently mutate and potentially become cancerous, but generally these cells are cleared by the immune system. The disease state of cancer arises when the mutated cells evade the immune clearance, which indicates medical intervention is required. Current therapies most commonly utilize chemotherapy, radiation, or a combination of the two, however, alternative therapies are being developed such as immunotherapies and oncolytic viruses (OVs). OVs cause a viral infection, clearing cancerous cells through viral replication mechanisms, such as viral cytolysis, while …
Effects Of Aging & Exercise On Production Of Glial Cell Line-Derived Neurotrophic Factor Protein By Fast & Slow Skeletal Muscle, Maria Jaramillo
Effects Of Aging & Exercise On Production Of Glial Cell Line-Derived Neurotrophic Factor Protein By Fast & Slow Skeletal Muscle, Maria Jaramillo
Honors Theses
Exercise is a positive form of reinforcing positive lifestyle choices. There are many benefits to exercising such as decreased risk of cardiovascular disease and improved mental condition (Centers for Disease Control and Prevention). In addition, exercise can serve a protecting role for the nervous system. One form in which exercise can protect the nervous system is by increasing the production of neurotrophic factors, specifically glial cell line-derived neurotrophic factor. Another way by which exercise can protect the nervous system is by preserving muscle tissue due to actively recruiting it. The goal of this study was to explore the effects of …
Gdf-15 As A Biomarker For Glaucoma, Caylee Pattison
Gdf-15 As A Biomarker For Glaucoma, Caylee Pattison
Honors Theses
Biomarkers are measurable substances in an organism that are indicative of some phenomenon. Examples of biomarkers in clinical settings are body temperature and blood pressure. Body temperature is indicative of a fever while blood pressure can be used to monitor someone’s risk of a stroke. Previous studies have investigated the possibility of there being a potential biomarker for glaucoma. One possible biomarker identified is growth differentiation factor 15 or GDF15. These studies prompted a study in our lab using a rat glaucoma model. The objective of this study was to show there is a biomarker present for the neurodegenerative disease, …