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Medicine and Health Sciences

University of Connecticut

2014

Chlorine

Articles 1 - 1 of 1

Full-Text Articles in Life Sciences

Effect Of Chlorine Exposure On The Survival And Antibiotic Gene Expression Of Multidrug Resistant Acinetobacter Baumannii In Water, Deepti Prasad Karumathil, Hsin-Bai Yin Feb 2014

Effect Of Chlorine Exposure On The Survival And Antibiotic Gene Expression Of Multidrug Resistant Acinetobacter Baumannii In Water, Deepti Prasad Karumathil, Hsin-Bai Yin

Open Access Author Fund Awardees' Articles

Acinetobacter baumannii is a multidrug resistant pathogen capable of causing a wide spectrum of clinical conditions in humans. Acinetobacter spp. is ubiquitously found in different water sources. Chlorine being the most commonly used disinfectant in water, the study investigated the effect of chlorine on the survival of A. baumannii in water and transcription of genes conferring antibiotic resistance. Eight clinical isolates of A. baumannii, including a fatal meningitis isolate (ATCC 17978) (~108 CFU/mL) were separately exposed to free chlorine concentrations (0.2, 1, 2, 3 and 4 ppm) with a contact time of 30, 60, 90 and 120 second. …