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Medicine and Health Sciences

The University of Notre Dame Australia

Cytokines

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Full-Text Articles in Life Sciences

The Role Of The Innate And Adaptive Immunity In Exercise Induced Muscle Damage And Repair, B Jones, G Hoyne Jan 2017

The Role Of The Innate And Adaptive Immunity In Exercise Induced Muscle Damage And Repair, B Jones, G Hoyne

Health Sciences Papers and Journal Articles

The immune system plays a crucial role in regulating tissue repair processes following damage. The cellular basis of tissue repair has best been studied in toxin-induced models due to their reliability and reproducible kinetics. These models have established a crucial role for innate and adaptive immune cells that follow a temporally regulated response that begins with a proinflammatory response that is subsequently replaced by a regulatory type 2 immune response to facilitate tissue repair and restore homeostasis. Inflammation is a crucial first response to cell damage that is modulated by the response of innate lymphoid cells and tissue resident regulatory …