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Articles 1 - 6 of 6
Full-Text Articles in Life Sciences
Identifying Molecular Pathways Underlying Noise-Induced Tinnitus, Mckenzie Rice
Identifying Molecular Pathways Underlying Noise-Induced Tinnitus, Mckenzie Rice
Williams Honors College, Honors Research Projects
Tinnitus is a serious neurological condition effecting 10-15% of adults, and can lead to other symptoms such as difficulty concentrating and sleeping, anxiety, and depression. Currently there are no FDA approved drugs to prevent or treat tinnitus, mainly due to a lack of understanding of its cellular and molecular pathways. T- and L- type calcium channels have been implicated in the modulation of tinnitus, as well as the dysfunction of gamma-aminobutyric acid (GABA) neurons. This study used the sound-based avoidance detection (SBAD) method in order to detect tinnitus and determine whether pharmacological treatments had an effect in mediating tinnitus. T-type …
Protocadherin-19 Expression And Function In Vertebrate Brain Review, Makana Mcguire
Protocadherin-19 Expression And Function In Vertebrate Brain Review, Makana Mcguire
Williams Honors College, Honors Research Projects
For this project, a systematic review will be conducted on published studies on protocadherin-19 expression and function in vertebrate central nervous system development in the last 10 years. Protocadherin-19 (pcdh19) is a member of the cadherin superfamily. Cadherins are calcium-dependent cell adhesion molecules show to play important roles in vertebrate tissue development including the formation of the central nervous system. Understanding molecular and cellular mechanisms underlying the function of pcdh19 will help aid in understanding disease(s) caused by malfunction of this molecule, and lead to potential strategies for treatment. Data will be collected via online search of databases. The project …
Analysis Of Circadian Rhythm Irregularities On The Health Of Shift Workers, Sahil Rajan
Analysis Of Circadian Rhythm Irregularities On The Health Of Shift Workers, Sahil Rajan
Williams Honors College, Honors Research Projects
Circadian rhythms involve the natural 24 wake-sleep cycle that governs proper maintenance of biological sleep schedules. Circadian rhythm disruption has been associated with health issues such as diabetes, obesity, and mental health disorders such as bipolar and sleep disorders. In this study, a survey method was utilized in order to analyze specific population demographics to determine whether working day or night shifts predisposed individuals to health issues due to disruptions in their circadian rhythms. This study was also carried out to observe popular coping strategies among night shift workers. Of all the variables tested comparing the difference between day and …
Role Of Vascular Endothelial Growth Factor Receptor 2 Pathway Due To Preeclampsia: A Review, Firdous Ali
Role Of Vascular Endothelial Growth Factor Receptor 2 Pathway Due To Preeclampsia: A Review, Firdous Ali
Williams Honors College, Honors Research Projects
Preeclampsia is a pregnancy complication that is characterized mainly by hypertension in the mother. The exact pathogenesis of preeclampsia is unknown, although the disease is attributed to a number of factors such as angiogenic factor levels and endothelial dysfunction. Presently, the control program for the disease involves the delivery of the fetus and the placenta. There is a need to develop novel therapies that would control preeclampsia from the moment it is diagnosed to minimize the effects on the mother and child. VEGF is a protein involved in the pathogenesis of the condition. The defect in one of its receptors, …
Sattvic Diet And All-Cause Mortality: A Systematic Review, Nrsimha Ghosh
Sattvic Diet And All-Cause Mortality: A Systematic Review, Nrsimha Ghosh
Williams Honors College, Honors Research Projects
A sattvic diet is a diet characterized by a moderate intake of food that is not reheated and is only eaten twice daily. It is mentioned in ancient Hindu scriptures such as the Srimad Bhagavad-gita. This paper aims to compare foods and habits considered to be sattvic with those considered to be rajasic and tamasic (those outside of the diet) in regard to all-cause mortality. Because of the many variable factors of all three diets, specific words mentioned in the texts were used to search Google Scholar, Agricola, Medline, Food Science Source, CINAHL Plus, Cochrane Library Online, PubMed, Health …
Impact Of Covid-19 On Ohio's National Parks Visitation, Ryan Grzeschik
Impact Of Covid-19 On Ohio's National Parks Visitation, Ryan Grzeschik
Williams Honors College, Honors Research Projects
The COVID-19 pandemic has fundamentally changed the way in which society operates in order to get the novel disease under control. Businesses throughout the United States have had to close or reduce provided services, stay at home orders have secluded many people, and social distancing limits contact between others so many are turning to the parks system to cope with these changes. This study aims to find how the visitation of national parks in Ohio have been affected through the first six months of the pandemic. Visitation statistics were compared from March to August of 2020 to those same months …