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The Effect Of Exercise On The Skeletal Muscle Phospholipidome Of Rats Fed A High-Fat Diet, Todd W. Mitchell, N. Turner, Paul Else, Anthony J. Hulbert, John Hawley, Jong Sam Lee, Clinton Bruce, Stephen J. Blanksby
The Effect Of Exercise On The Skeletal Muscle Phospholipidome Of Rats Fed A High-Fat Diet, Todd W. Mitchell, N. Turner, Paul Else, Anthony J. Hulbert, John Hawley, Jong Sam Lee, Clinton Bruce, Stephen J. Blanksby
Stephen Blanksby
The aim of this study was to examine the effect of endurance training on skeletal muscle phospholipid molecular species from high-fat fed rats. Twelve female Sprague- Dawley rats were fed a high-fat diet (78.1% energy). The rats were randomly divided into two groups, a sedentary control group and a trained group (125 min of treadmill running at 8 m/min, 4 days/wk for 4 weeks). Forty-eight hours after their last training bout phospholipids were extracted from the red and white vastus lateralis and analyzed by electrospray-ionization mass spectrometry. Exercise training was associated with significant alterations in the relative abundance of a …