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Medicine and Health Sciences

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Articles 1 - 5 of 5

Full-Text Articles in Life Sciences

Olanzapine Treatment And Time-Dependent Changes Of Hypothalamic Ampk-Acc-Cpt1 Signalling, Food Intake And Body Weight In Rats, Meng He, Q Zhang, H Wang, Jiamei Lian, C Deng, Xu-Feng Huang Apr 2013

Olanzapine Treatment And Time-Dependent Changes Of Hypothalamic Ampk-Acc-Cpt1 Signalling, Food Intake And Body Weight In Rats, Meng He, Q Zhang, H Wang, Jiamei Lian, C Deng, Xu-Feng Huang

Xu-Feng Huang

No abstract provided.


Neuropeptide Y Mrna Expression Levels Following Chronic Olanzapine, Clozapine And Haloperidol Administration In Rats, Xu-Feng Huang, Katerina Zavitsanou, Chao Deng Sep 2012

Neuropeptide Y Mrna Expression Levels Following Chronic Olanzapine, Clozapine And Haloperidol Administration In Rats, Xu-Feng Huang, Katerina Zavitsanou, Chao Deng

Xu-Feng Huang

No abstract provided.


Perinatal Administration Of Pcp Alters Adult Behaviour In Female Sprague-Dawley Rats, Teresa Du Bois, Xu-Feng Huang, Chao Deng Sep 2012

Perinatal Administration Of Pcp Alters Adult Behaviour In Female Sprague-Dawley Rats, Teresa Du Bois, Xu-Feng Huang, Chao Deng

Xu-Feng Huang

Perinatal phencyclidine (PCP) treatment leads to neuronal damage and causes long-term behavioural alterations in rodents. This study examined the effects of perinatal PCP treatment on behaviour of adult rats in holeboard, elevated plus maze, social interaction and forced swim tests. PCP-treated rats displayed hyperactivity in the holeboard and forced swim tests. These persistent behavioural changes are relevant to the study of psychiatric disorders such as schizophrenia.


Dietary Shiitake Mushroom (Lentinus Edodes) Prevents Fat Deposition And Lowers Triglyceride In Rats Fed A High-Fat Diet, D Handayani, J-Z Chen, Barbara Meyer, Xu-Feng Huang Sep 2012

Dietary Shiitake Mushroom (Lentinus Edodes) Prevents Fat Deposition And Lowers Triglyceride In Rats Fed A High-Fat Diet, D Handayani, J-Z Chen, Barbara Meyer, Xu-Feng Huang

Xu-Feng Huang

High-fat diet (HFD) induces obesity. This study examined the effects of Shiitake mushroom on the prevention of alterations of plasma lipid profiles, fat deposition, energy efficiency, and body fat index induced by HFD. Rats were given a low, medium, and high (7, 20, 60 g/kg = LD-M, MD-M, HD-M) Shiitake mushroom powder in their high-fat (50% in kcal) diets for 6 weeks. The results showed that the rats on the HD-M diet had the lowest body weight gain compared to MD-M and LD-M groups (P < 0.05). The total fat deposition was significantly lower (-35%, P < 0.05) in rats fed an …


Purification Of The Golgi Adenosine 3'-Phosphate 5'-Phosphosulfate Transporter, A Homodimer Within The Membrane, Elisabet Mandon, Marcos Milla, Ellis Kempner, Carlos Hirschberg Feb 2012

Purification Of The Golgi Adenosine 3'-Phosphate 5'-Phosphosulfate Transporter, A Homodimer Within The Membrane, Elisabet Mandon, Marcos Milla, Ellis Kempner, Carlos Hirschberg

Elisabet Mandon

Sulfation of proteoglycans, secretory and membrane proteins, and glycolipids occurs in the lumen of the Golgi apparatus. Adenosine 3'-phosphate 5'-phosphosulfate (PAPS), the sulfate donor in these reactions, must be transported from the cytosol, its site of synthesis, into the lumen of the Golgi apparatus. We have identified and purified to apparent homogeneity the rat liver Golgi membrane PAPS transporter by a combination of conventional and affinity chromatography as well as photoaffinity radiolabeling with adenosine 3',5'-bisphosphate, a competitive inhibitor of PAPS transport. The transporter, a 75-kDa protein, was purified 70,000-fold over homogenate (6% yield) and transported PAPS into phosphatidylcholine liposomes selectively …