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Medicine and Health Sciences

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Karen E. Charlton

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Full-Text Articles in Life Sciences

Start Date May Predict Attrition 6 Months Into A 12mth Dietary Intervention Weight Loss Trial, Jane O'Shea, Linda Tapsell, Marijka Batterham, Karen Charlton, Yasmine Probst, Rebecca Thorne, Qingsheng Zhang, Holley Jones Apr 2013

Start Date May Predict Attrition 6 Months Into A 12mth Dietary Intervention Weight Loss Trial, Jane O'Shea, Linda Tapsell, Marijka Batterham, Karen Charlton, Yasmine Probst, Rebecca Thorne, Qingsheng Zhang, Holley Jones

Karen E. Charlton

Participant recruitment is a difficult and time consuming aspect of clinical trials, often resulting in delays and budget overruns. Having reached recruitment targets the next challenge is participant retention. Some weight-loss studies have attrition rates around 60% which may introduce bias in the results. It may be possible to reduce attrition rates if known predictors can be found but to date few studies produced consistent results. The aim of this exploratory study was to determine whether start date could be a predictor of attrition for participants involved in the SMART weight loss clinical trial (ACTRN12608000425392). Recruitment for the trial occurred …


Associations Between Baseline Erythrocyte N-3 Polyunsaturated Fatty Acids And Weight Indices In Volunteers For A Weight Loss Dietary Intervention, Linda Tapsell, J O'Shea, M Batterham, K Charlton, E Warensjo, R Thorne, K Zhang Apr 2013

Associations Between Baseline Erythrocyte N-3 Polyunsaturated Fatty Acids And Weight Indices In Volunteers For A Weight Loss Dietary Intervention, Linda Tapsell, J O'Shea, M Batterham, K Charlton, E Warensjo, R Thorne, K Zhang

Karen E. Charlton

No abstract provided.


Short Term Effects Of Energy Restriction And Dietary Fat Sub-Type On Weight Loss And Disease Risk Factors, Linda C. Tapsell, Marijka Batterham, Xu-Feng Huang, Sze Yen Tan, Grigorijs Teuss, Karen E. Charlton, Jane E. O'Shea, Eva M. Warensjo Apr 2013

Short Term Effects Of Energy Restriction And Dietary Fat Sub-Type On Weight Loss And Disease Risk Factors, Linda C. Tapsell, Marijka Batterham, Xu-Feng Huang, Sze Yen Tan, Grigorijs Teuss, Karen E. Charlton, Jane E. O'Shea, Eva M. Warensjo

Karen E. Charlton

Background and aims: Decreasing energy intake relative to energy expenditure is the indisputable tenet of weight loss. In addition to caloric restriction modification of the type of dietary fat may provide further benefits. The aim of the present study was to examine the effect of energy restriction alone and with dietary fat modification on weight loss and adiposity, as well as on risk factors for obesity related disease. Methods and results: One-hundred and fifty overweight men and women were randomized into a 3 month controlled trial with four low fat (30% energy) dietary arms: (1) isocaloric (LF); (2) isocaloric with …