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Life Sciences Commons

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Medicine and Health Sciences

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UCHC Articles - Research

2011

Biologic markers

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Full-Text Articles in Life Sciences

Prevalence And Prognostic Role Of Triple-Negative Breast Cancer By Race: A Surveillance Study, Helen Swede, David I. Gregorio, Susan H. Tannenbaum, Jessica A. Brockmeyer, Lori L. Wilson, Mellisa A. Pensa, Richard G. Stevens, Carolyn D. Runowicz Oct 2011

Prevalence And Prognostic Role Of Triple-Negative Breast Cancer By Race: A Surveillance Study, Helen Swede, David I. Gregorio, Susan H. Tannenbaum, Jessica A. Brockmeyer, Lori L. Wilson, Mellisa A. Pensa, Richard G. Stevens, Carolyn D. Runowicz

UCHC Articles - Research

A possible explanation for the relatively poor survival from breast cancer among blacks is the much higher rate of the adverse Triple-Negative sub-type. In a study of 1372 patients, blacks had twice the risk of death compared to whites among those with advanced cancer whether or not tumors were Triple-Negative. More research is still warranted to determine why blacks with advanced, but not local, breast cancer have a consistently higher rate of death.

Introduction

Emerging research suggests a substantially greater prevalence of the adverse triple-negative (TN) subtype (human epidermal growth factor receptor [HER]2, estrogen receptor [ER], …