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Multigenerational Consequences Of Environment And Loss On Maternal Behavior, Anxiety, Boldness, And Memory In Rats, Alayna Palamar
Multigenerational Consequences Of Environment And Loss On Maternal Behavior, Anxiety, Boldness, And Memory In Rats, Alayna Palamar
Longwood Senior Theses
Maternal behavior has long been studied for the implications it presents for offspring outcomes. In the present study, we examined the interplay between the positive effects of environmental enrichment and the negative consequences of loss – defined as a 50% litter cull – on both mothers and their offspring. In this multigenerational study, maternal Sprague Dawley rats were separated into one of four of the following conditions: enriched/control, enriched/loss, standard/control, and standard/loss. Maternal rats (P generation) were assessed using the following behavioral assays: Elevated Plus Maze (EPM) for anxiety-like behavior and boldness, Object Location Maze (OLM) for spatial memory, and …