Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
Pet Imaging Of Early Therapeutic Response In Solid Tumors, Stephanie J. Blocker
Pet Imaging Of Early Therapeutic Response In Solid Tumors, Stephanie J. Blocker
Wayne State University Dissertations
An important pillar of precision medicine for oncology is the ability to identify patients who respond to treatment early into their therapy. Positron emission tomography (PET) allows physicians and researchers to measure changes in tumor behavior prior to noticeable differences in morphology.
Objective: Determine the utility of multiple tracers for PET in assessing early changes in tumor activity that result from treatment.
Methods: Two tracers for PET were studied. 64Cu-labeled liposomes were used to assess changes in liposome delivery two solid colon tumors early into treatment with bevacizumab (Bev). 18F-FMAU thymidine analog (1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)thymine), was utilized to detect early response to …