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Emerging Role Of Garcinol, The Antioxidant Chalcone From Garcinia Indica Choisy And Its Synthetic Analogs, Subhash Padhye, Aamir Ahmad, Nikhil Oswal, Fazlul H. Sarkar

Wayne State University Associated BioMed Central Scholarship

Abstract

Garcinol, harvested from Garcinia indica, has traditionally been used in tropical regions and appreciated for centuries; however its biological properties are only beginning to be elucidated. There is ample data to suggest potent antioxidant properties of this compound which have been used to explain most of its observed biological activities. However, emerging evidence suggests that garcinol could be useful as an anti-cancer agent, and it is increasingly being realized that garcinol is a pleiotropic agent capable of modulating key regulatory cell signaling pathways. Here we have summarized the progress of our current research knowledge on garcinol and its observed …