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Full-Text Articles in Life Sciences
Patient Knowledge Of Family History Of Cardiac Events And Risk Factors: Potential For Increase In Preventative Care Of Cardiovascular Diseases, Joseph Marentette
Patient Knowledge Of Family History Of Cardiac Events And Risk Factors: Potential For Increase In Preventative Care Of Cardiovascular Diseases, Joseph Marentette
Honors Theses
The following literature review regards the preventative care of cardiovascular disease (CVD) patients with the knowledge of familial cardiac events and personal cardiac risk factors, particularly in younger populations ranging from ages 18 to 39, and develop potential preventative care measures. CVD is preventable with early reduction of risk factors. People can lower the impact of cardiac risk factors through the modification of their current lifestyle and behavioral habits. However, this is limited to the education and motivation of the person. Primary emphasis must be placed on community education and physician-patient interactions regarding CVD and cardiac risk factors. Physicians need …
The Impacts Of Aging, Sedentarism, And Exercise On Neurotrophic Factor Expression And Innervation In The Heart And The Effects Of Treatment With Α-Cgrp On Heart Function, Gabriel Almeida Alves
The Impacts Of Aging, Sedentarism, And Exercise On Neurotrophic Factor Expression And Innervation In The Heart And The Effects Of Treatment With Α-Cgrp On Heart Function, Gabriel Almeida Alves
Dissertations
Neurotrophic factors (NFs) are important molecules responsible for development, differentiation, regeneration, and maintenance of new and mature neurons. Neurotrophic factors act as neurocytokines and may assist with the regulation of axonal and dendritic arrangements and synaptic plasticity between neurons themselves or with other non-neural target tissues. In this study, we analyze the levels of two NFs: glial cell line-derived neurotrophic factor (GDNF) and nerve growth factor (NGF). Cardiomyocytes produce these neurotrophic factors which assist with the innervation pattern of the heart. The heart is innervated by the two branches of the autonomic nervous system; namely the sympathetic nervous system and …
Organized Caudal Photoreceptors In The Medicinal Leech, Baylee Bancroft
Organized Caudal Photoreceptors In The Medicinal Leech, Baylee Bancroft
Honors Theses
Visual systems are essential to an organism’s survival. There are a wide range of photosensory organs across the animal kingdom, varying by means of structure, complexity, and the way in which they transduce information. Regardless of variation, visual systems provide the organism with information regarding external stimuli based on how light interacts with surrounding matter. The medicinal leech, Hirudo verbana, is one of the many important model organisms of neurobiology as this segmented annelid possesses a relatively simple nervous system and a rudimentary visual system. The leech also exhibits a restricted range of quantifiable overt behaviors and is capable of …
Relationship Between One Repetition Maximum Parallel Squat And Jump Squat Peak Power, Corey Klitzke
Relationship Between One Repetition Maximum Parallel Squat And Jump Squat Peak Power, Corey Klitzke
Masters Theses
Jump squats are a simple exercise that can be used to train lower body power. Unlike many other methods of power training, jump squats do not require any specialized equipment (platforms, bumper plates, etc.). Jump squats can be used when other forms of power training are not available or are not allowed. In order to most efficiently train power, the intensity must balance force and velocity. The purpose of this study was to find the intensity that yields the peak power output of a jump squat. 12 participants (9 males, 3 female) participated in the study. Each participant completed a …
The Correlation Between The Microbiome And Neurodegenerative Disorders Such As Alzheimer Disease, Aurora Mokris
The Correlation Between The Microbiome And Neurodegenerative Disorders Such As Alzheimer Disease, Aurora Mokris
Honors Theses
Recent studies suggest that there are 1.3 times as many microbial cells as human cells in the body (Abbot, 2016). Another study claims that the combined genomes of this microbiota is 150 times that of the human genome (Zhuang & Shen, 2018). If you have ever had the feeling that you are not alone in an empty room you are most certainly correct. Your body is teeming with millions of organisms living in mutualistic symbiosis with you and surrounding microbes, but at times, this seemingly harmonious relationship can be disturbed, resulting in serious physical and psychological changes to the human …
Antegrade Endosteal Fibular Strut Augmentation For Periprosthetic Femur Fracture Above Stemmed Total Knee Arthroplasty, Tyler Snoap, Jason Roberts, Matthew Jaykel
Antegrade Endosteal Fibular Strut Augmentation For Periprosthetic Femur Fracture Above Stemmed Total Knee Arthroplasty, Tyler Snoap, Jason Roberts, Matthew Jaykel
Research Day
Abstract Title: ANTEGRADE ENDOSTEAL FIBULAR STRUT AUGMENTATION FOR PERIPROSTHETIC FEMUR FRACTURE ABOVE STEMMED TOTAL KNEE ARTHROPLASTY Abstract ID: 245 Abstract Category: Clinical Research Introduction: The management of peri-prosthetics fracture around total knee replacements is technically challenging. The options for operative fixation become more limited if the femoral component is stemmed, which often is the case after revision arthroplasty procedures. The goals of surgery for peri-prosthetic fractures above knee replacements are to provide a rigid construct to promote healing, allow immediate knee range of motion, and allow weight bearing during the healing process. Purpose: The purpose of this study is to …
First 100 Cases Of Bls First Responder A Dministered Naloxone In A Statewide Ems System, Joshua Mastenbrook, James Markman, Tyler Koedam, William Fales
First 100 Cases Of Bls First Responder A Dministered Naloxone In A Statewide Ems System, Joshua Mastenbrook, James Markman, Tyler Koedam, William Fales
Research Day
Abstract Title: FIRST 100 CASES OF BLS FIRST RESPONDER ADMINISTERED NALOXONE IN A STATEWIDE EMS SYSTEM Abstract ID: 240 Abstract Category: Clinical Research BACKGROUND: In October 2015, a midwestern state law mandated that all BLS first responder (FR) agencies be trained and equipped to administer naloxone to suspected opioid-overdose patients. Although well intentioned, several questions have arisen: does naloxone use displace emphasis on early positive pressure ventilation (PPV), is naloxone being appropriately administered, and does the mandate affect patient outcome. The purpose of this study is to evaluate the first 100 cases of FR administered naloxone (FR-naloxone) for administration appropriateness …
A Case Of Difficult-To-Treat Asthma Due To Uncontrolled Atypical Gastroesophageal Reflux, Alissa Welsh, Andrey Leonov
A Case Of Difficult-To-Treat Asthma Due To Uncontrolled Atypical Gastroesophageal Reflux, Alissa Welsh, Andrey Leonov
Research Day
Introduction: In uncontrolled asthma, comorbid conditions should be treated in order to achieve better asthma control. The contribution of gastro-esophageal reflux (GER) may be overlooked when its presentation is atypical. Case Report: 11 year-old male with moderate persistent asthma and allergic rhinitis presented with persistent barky cough, diagnosed as spasmodic croup after bronchoscopy, esophagram, swallow study and magnified airway x-ray failed to show anatomical abnormality. Empiric proton pump inhibitor (PPI) treatment was started with improvement in cough. Patient was referred to Gastroenterology for evaluation of GER, despite lack of heartburn or vomiting. Endoscopy revealed esophageal candida infection which was treated. …
Traumatic Laceration Of The Posterior Tibial Tendon Treated With Novel Technique, Nicholas Miladore, Robert Gorman
Traumatic Laceration Of The Posterior Tibial Tendon Treated With Novel Technique, Nicholas Miladore, Robert Gorman
Research Day
Abstract Title: TRAUMATIC LACERATION OF THE POSTERIOR TIBIAL TENDON TREATED WITH NOVEL TECHNIQUE Abstract ID: 249 Abstract Category: Clinical Research INTRODUCTION: Posterior tibial tendon (PTT) insufficiency is a common entity, and can result in chronic tendon disruption. Acute disruption is a rare occurrence, but has been described in the literature. Most reported cases are associated with ipsilateral ankle fractures. Laceration of the posterior tibial tendon has also been described, typically in the operative setting as a result of iatrogenic injury. CASE REPORT: A 15 year old male presented to the clinic with complaints of right ankle pain and weakness. 2.5 …
Gallbladder Duplication: Case Report Of A Rare Congenital Anomaly Treated By Single-Incision Laparoscopic Cholecystectomy In A Pediatric Patient, Jairo Espinosa M.D., Peter White, Michael Leinwand M.D.
Gallbladder Duplication: Case Report Of A Rare Congenital Anomaly Treated By Single-Incision Laparoscopic Cholecystectomy In A Pediatric Patient, Jairo Espinosa M.D., Peter White, Michael Leinwand M.D.
Research Day
Introduction: Gallbladder duplication is a rare congenital anomaly. Preoperative diagnosis is essential for prevention of intra operative complications. Based on our review of the literature, this is the first description of gallbladder duplication treated with single-incision laparoscopic surgery (SILS) in a pediatric patient. Case Presentation: A 14 year-old girl presented to the pediatric surgery clinic with a 4-month history of right upper quadrant abdominal pain, nausea, and low- grade fevers. Preoperative imaging revealed gallbladder duplication. The single incision laparoscopic technique was employed. Intra operative ndings included two gallbladders that appeared to share a common wall. There were two parallel cystic …
A Highly Unusual Case Of Metastatic Pancreatic Adenocarcinoma, Zachary Koehn, Lauren Piper
A Highly Unusual Case Of Metastatic Pancreatic Adenocarcinoma, Zachary Koehn, Lauren Piper
Research Day
Introduction: Pancreatic cancer is a rare malignancy, with nearly a 100% mortality rate. The strongest risk factor for pancreatic cancer is advanced age; the median age of diagnosis is 70. Here we discuss a case of pancreatic cancer in a 32 year-old woman. Case Description: S.R. is a 32 year-old female presenting with new-onset jaundice. Two months prior to presentation, she reported vomiting and LUQ pain, and was treated for H. pylori. Her symptoms improved, but she developed anorexia, RUQ pain, 35 lb weight loss and clay-colored diarrhea. Her medical history is negative except for 10-pack-year smoking history. Exam revealed …
Mixed Goblet Cell Carcinoid-Adenocarcinoma: A Case Series, Jairo Espinosa M.D., Timothy Truong, Julia Miladore M.D., John T. Collins, Saad Shebrain M.D., Gitonga Munene M.D.
Mixed Goblet Cell Carcinoid-Adenocarcinoma: A Case Series, Jairo Espinosa M.D., Timothy Truong, Julia Miladore M.D., John T. Collins, Saad Shebrain M.D., Gitonga Munene M.D.
Research Day
INTRODUCTION: Mixed goblet cell carcinoid-adenocarcinoma (GCC) tumors are a group of rare heterogenous neoplasms of the appendix accounting for < 5% of all primary appendiceal tumors. They are characterized as an intermediate between classic carcinoid tumors and appendiceal adenocarcinomas, exhibiting both neuroendocrine and glandular/mucinous morphology that most commonly presents in Caucasian females in the fifth and sixth decades. We present three cases of mixed GCC presenting as acute appendicitis. CASE PRESENTATION: Case #1 A 65-year-old male presented with RLQ pain, nausea, emesis, and leukocytosis. CT of the abdomen revealed perforated appendicitis. The patient underwent a laparoscopic appendectomy. Pathology revealed a high-grade adenocarcinoma ex goblet cell carcinoid, signet ring type extending through the muscularis propria into the mesoappendix measuring >3cm. The patient subsequently underwent a colonoscopy that revealed diverticulosis, but was otherwise normal. Patient then underwent a right hemicolectomy and partial omentectomy. Pathology revealed normal ileal, omental, and colonic tissue without evidence of carcinoma. 0/12 nodes were positive. Case #2 A 49-year-old male presented with periumbilical pain, nausea, emesis, and leukocytosis. CT of the abdomen revealed appendicitis. The patient underwent a laparoscopic appendectomy. Pathology revealed a high-grade, poorly differentiated, adenocarcinoma ex goblet cell carcinoid invading through the muscularis propria into …
16 Year Old Baseball Pitcher Presenting With Gradual Worsening Of Posterolateral Right Elbow Pain And Negative Mri Findings, Nithin Natwa, Reema Sheth, Nisha Sheth
16 Year Old Baseball Pitcher Presenting With Gradual Worsening Of Posterolateral Right Elbow Pain And Negative Mri Findings, Nithin Natwa, Reema Sheth, Nisha Sheth
Research Day
Background: Elbow pain is a common presenting symptom in repetitive motion performing athletes. Due to the popular use of prolonged conservative therapy in elbow pain, and the importance of early surgical intervention in Elbow Synovial Fold Syndrome, proper and prompt diagnosis is essential. In our case report, a 16 year old male right hand-dominant baseball pitcher presents with gradual onset of posterolateral right elbow pain over 4 months. Purpose: This study helps reflect the correct timeline in imaging along with the appropriate duration of conservative management. After reviewing this study the reader will be better able to differentiate between Lateral …
Rare Presentation Of High Grade Retroperitoneal Angiosarcoma In A Patient Status Post Endovascular Aortic Repair (Evar), Jairo Espinosa M.D., Alan Hifko, Julia Miladore M.D., John T. Collins
Rare Presentation Of High Grade Retroperitoneal Angiosarcoma In A Patient Status Post Endovascular Aortic Repair (Evar), Jairo Espinosa M.D., Alan Hifko, Julia Miladore M.D., John T. Collins
Research Day
INTRODUCTION: Primary angiosarcoma of the aorta is a rare malignancy arising from the aorta’s endothelial lining. The most common presentation is claudication, however in the presence of an endograft a tumor originating in the aneurysmal sac may remain undetected and mimic common graft pathology. Diagnosis is typically delayed due to vague clinical presentation and imaging being indistinguishable from common complications of endografts such as leaks, infections or hematomas. We report a case of primary angiosarcoma of the aorta after endovascular repair of an abdominal aortic aneurysm. This case report describes the sixth case in the literature of primary angiosarcoma arising …
A Case Of Successful Treatment Of Skin Excoriation Disorder With N-Acetyl Cysteine, Nauman Khan M.D., Priya Mahajan M.D., Sadia Shaukat M.D., Matthew Lacasse D.O., Mark Kanzawa D.O.
A Case Of Successful Treatment Of Skin Excoriation Disorder With N-Acetyl Cysteine, Nauman Khan M.D., Priya Mahajan M.D., Sadia Shaukat M.D., Matthew Lacasse D.O., Mark Kanzawa D.O.
Research Day
Introduction: We present a case of a middle age patient with skin excoriation disorder since age 15 who experienced significant improvement with augmentation of her treatment regimen with N-acetyl cysteine. This improvement occurred despite a recurrence of her depression, alcohol use disorder, and stimulant use disorder. Case Presentation: A 59 year-old-female with 44 years of unsuccessful treatment of self-excoriation disorder presented with symptoms of unspecified depression, OCD and stimulant use disorder. She was referred by her surgeon who had to postpone a revision of her hip replacement as she was self-excoriating the right axillary lymphadenectomy site. Initial administration of PHQ-9 …
Cryptococcal Empyema: A Rare Manifestation Of Disease, Mohamed Mortagy, Larry Lutwick, Stephen Breisach
Cryptococcal Empyema: A Rare Manifestation Of Disease, Mohamed Mortagy, Larry Lutwick, Stephen Breisach
Research Day
Introduction: Cryptococcus neoformans is a pathogenic yeast that is generally acquired by man from the environment via the respiratory route. Despite this route of acquisition, overt pulmonary infection is uncommonly diagnosed and the disease is usually manifest as a subacute meningitis which is mostly manifest in individuals who are celluarly immunoincompetent such as those on cancer chemotherapy, receiving anti-solid organ rejection medications and those with HIV/AIDS. Infection of the pleural space with C. neoformans is quite uncommon. We report a non-immunosuppressed man who was found to have infection of the pleural in the wake of bacterial empyema who was successfully …
Infection-Associated Mycobacterium Fortuitum Infection, Dennis T. Huang, Larry Lutwick
Infection-Associated Mycobacterium Fortuitum Infection, Dennis T. Huang, Larry Lutwick
Research Day
Introduction: Mycobacterial species are unusual causes of skin and soft tissue infections and can be difficult to diagnose in the absence of consideration as they often require specific culture media and longer incubation times. We report a Mycobacterium fortuitum subcutaneous abscess in a diabetic related to medication injection that was initially diagnosed without specialized media or prolonged incubation times. Case Report: A 48 year old diabetic female developed a progressive subcutaneous swelling in the tissues of the right lower abdominal wall where she had been injecting liraglutide. Because of continued enlargement "to almost egg size" with pain, she was empirically …
Acute Hypoxic Respiratory Failure As A Complication Of A Urinary Tract Infection During Pregnancy: A Case Presentation, Manpreet S. Narwal, Susan Jevert-Eichorn, Narinder Nina Clair
Acute Hypoxic Respiratory Failure As A Complication Of A Urinary Tract Infection During Pregnancy: A Case Presentation, Manpreet S. Narwal, Susan Jevert-Eichorn, Narinder Nina Clair
Research Day
Urinary tract infections (UTI), as well as asymptomatic bacteriuria, have the potential to cause serious morbidity during pregnancy making it imperative to identify and treat them promptly. If left untreated, a UTI can lead to pyelonephritis and sepsis. More importantly, UTIs are independently associated with intrauterine growth restriction (IUGR), premature rupture of membranes (PROM), preterm delivery, pulmonary edema, acute respiratory distress syndrome (ARDS), preeclampsia, and cesarean delivery. We report the case of NC, a 19 year old G1P0 at 36 weeks and 3 days GA who presented to the hospital with concern for rupture of membranes with associated back and …
Social Determinants - Impacting Or Causing Disparities In Patient Care?, Shaena Faye Freeman Md, Kristi Vanderkolk Md
Social Determinants - Impacting Or Causing Disparities In Patient Care?, Shaena Faye Freeman Md, Kristi Vanderkolk Md
Research Day
Health disparities secondary to social factors including socioeconomic status, race, gender and ethnicity are well known to the health community and are a troubling issue in the United States. Social determinants are defined by the WHO as the structural “conditions people are born, live, grow, work and age in…determined by wealth distribution and available resources…that are mostly responsible for health inequalities.” We present here the case of TL, a 49 year old African American female who presented to the emergency department three times with atypical coronary disease symptoms in the setting of recent NSTEMI with subsequent 3 vessel CABG. At …
Widening The Differential: A Case Of Hemophagocytic Lymphohistiocytosis Disguised As A Fever Of Unknown Origin, Emily Cordes
Widening The Differential: A Case Of Hemophagocytic Lymphohistiocytosis Disguised As A Fever Of Unknown Origin, Emily Cordes
Research Day
Introduction: Hemophagocytic lymphohistiocytosis (HLH) is an under recognized, aggressive inflammatory disease characterized by excessive activity of histiocytes and lymphocytes. According to the HLH-2004 guidelines, five of the following eight criteria must be met to diagnose HLH: fever >38.5¡ã C, splenomegaly; cytopenias affecting ¡Ý two cell lines; hypertriglyceridemia/hypofibrinogenemia; evidence of hemophagocytosis in the bone marrow, spleen or lymph nodes; hyperferritinemia; low NK cell activity; or high levels of soluble CD25. Once a diagnosis of HLH is established, investigations for infectious, malignant or autoimmune etiologies must be pursued. We report a case of fever of unknown origin (FUO) that presented multiple times …
A Case Of Native Valve Staphylococcus Epidermidis Endocarditis With Cardiac Abscess Formation, Emily Cordes, Chris Jacob, Mark Loehrke
A Case Of Native Valve Staphylococcus Epidermidis Endocarditis With Cardiac Abscess Formation, Emily Cordes, Chris Jacob, Mark Loehrke
Research Day
Introduction: Staphylococcus epidermidis is the most common commensal bacteria of the skin; however it can be pathogenic and is the most frequent cause of medical device associated endocarditis. It is also a well-known cause of endocarditis in IV drug abuse (IVDA). However, in individuals without obvious disruption of the skin barrier, it is a relatively rare, but emerging entity of native valve endocarditis. Coagulase negative staphylococci account for only 1-5% of community acquired native valve infective endocarditis and most resolve with treatment. We report a case of a 56 year old male with an aggressive strain of community acquired Staphylococcus …
Death Related To Fistulas Involving The Gastrointestinal And Cardiovascular Systems, Allan Joseph Medwick Edd, Joseph Prahlow
Death Related To Fistulas Involving The Gastrointestinal And Cardiovascular Systems, Allan Joseph Medwick Edd, Joseph Prahlow
Research Day
BACKGROUND/INTRODUCTION: Gastrointestinal tract fistulas are relatively uncommon and can be congenital or acquired. Fistulas may communicate with a variety of anatomic locations, including body cavities, the skin, and other organ systems. Acquired fistulas which communicate with the cardiovascular system are of particular concern, as they may be associated with significant morbidity and mortality. This study reports on three cases of acquired, post-surgical fistula formation involving the gastrointestinal and cardiovascular systems. CASE REPORTS: Case 1 - A 57-year-old man experienced sudden cardiac death shortly after having a permanent pacemaker placed for atrial fibrillation. Approximately two years earlier, he underwent surgical resection …
Benefit Of Ultrasound Curriculum Development For Family Medicine Residents, Nithin Natwa, Uzair Munshey, Duncan Vos, Robert Baker
Benefit Of Ultrasound Curriculum Development For Family Medicine Residents, Nithin Natwa, Uzair Munshey, Duncan Vos, Robert Baker
Research Day
Introduction/Purpose: Musculoskeletal problems comprise some of the most common reasons for ambulatory care encounters in the United States, accounting for 8.3% of the 1.2 billion visits per year according to the CDC. Musculoskeletal Ultrasound use has become more common in primary care for diagnosis and therapeutics. In Family Medicine Residency (FMR) Programs there is a deficiency of a structured, competency-based musculoskeletal ultrasound (MSK US) training despite its growing popularity. Currently, there is no formalized requirement for Ultrasound education as in other residency programs in spite of its benefit. Methods: We received a positive response on our needs analysis survey for …
Acquired Craniosynostosis In A Patient With Iatrogenic Vitamin D Intoxication, Wesley Eichorn, Kristi Vanderkolk Md
Acquired Craniosynostosis In A Patient With Iatrogenic Vitamin D Intoxication, Wesley Eichorn, Kristi Vanderkolk Md
Research Day
Introduction: Craniosynostosis, which refers to premature fusion of cranial sutures, is an uncommon diagnosis in the pediatric patient, occurring with an incidence of approximately 1 in 2,000 individuals. It is most often associated with X-Linked hypophosphatemic rickets. The implications of craniosynostosis, especially with a delayed diagnosis, are severe. Case Report: MJ is an African American male born at term via cesarean section with an unremarkable immediate postnatal period. He was diagnosed with rickets at the age of 7 months but treatment was not immediately initiated. He presented again at age 9 months with an upper respiratory infection and failure to …
Childhood Idiopathic Pulmonary Hypertension: A Case Report, Nathaniel Balmert, Joseph Prahlow
Childhood Idiopathic Pulmonary Hypertension: A Case Report, Nathaniel Balmert, Joseph Prahlow
Research Day
Introduction: Pulmonary arterial hypertension (PAH) is characterized as average pulmonary artery pressure of greater than 25mm Hg at rest. Childhood idiopathic pulmonary hypertensions (CIPH) is distinguishable from PAH by the absence of family history or underlying disease. Symptoms of CIPH include dyspnea, exercise limitation, and syncope. Common organ-specific changes include right ventricular hypertrophy and right ventricular strain. We present the case of a 6-year-old girl presenting with idiopathic pulmonary arterial hypertension aggravated by esophageal intubation. Methods: This case is from the files of one of the authors, a forensic pathologist. Case Report and Discussion: Diagnosed with pulmonary arterial hypertension when …
Utility Of Fern Test To Determine Rupture Of Membranes, Wesley Eichorn, Susan Jevert-Eichorn
Utility Of Fern Test To Determine Rupture Of Membranes, Wesley Eichorn, Susan Jevert-Eichorn
Research Day
Introduction: The fern test was first described by Kardos and Tamasi in 1955 as a test used to determine rupture of amniotic membranes. The test is done by collection of fluid from the vagina which is then allowed to dry for 10 minutes on a slide. The slide is then inspected with microscopy for evidence of ferning. Accurate determination of rupture of membranes is important due to its significant implications on the management of obstetrical patients. Case: EC is a 23 year old G1P0 at 40 and 3/7 weeks gestation who presented to an outpatient facility with a chief complaint …
Improving Productivity Through Scheduling At The Wmed Family Medicine Residency Clinic, Alex Witte Md, Susan Jevert-Eichorn, Alison Radigan Md, Larry Mann Do, Jamie Mccartney Md, Aisha Shakoor Md
Improving Productivity Through Scheduling At The Wmed Family Medicine Residency Clinic, Alex Witte Md, Susan Jevert-Eichorn, Alison Radigan Md, Larry Mann Do, Jamie Mccartney Md, Aisha Shakoor Md
Research Day
INTRODUCTION: The Accreditation Council for Graduate Medical Education (ACGME) requires every family medicine residency program to have a practice site that supports, “continuous, comprehensive, convenient, accessible, and coordinated patient care”. The WMed Family Medicine Resident Clinic (Team Oakland), located within the Family Health Center (FHC) – Paterson location, has long been plagued by scheduling difficulties, as evidenced by high no-show rates, empty appointment slots, and frequent cancellations threatening the ability of our residents to achieve the required number of outpatient visits mandated by the Family Medicine Residency Review Committee (RRC) and the requirement for continuity from the ACGME. We believe …
Surviving As A Cancer Survivor: A Case Report Of Radiation-Induced Autonomic Dysfunction, Daphne Sy, Mark Schauer
Surviving As A Cancer Survivor: A Case Report Of Radiation-Induced Autonomic Dysfunction, Daphne Sy, Mark Schauer
Research Day
While radiation and chemotherapy have achieved high rates of cure for Hodgkin lymphoma, the medical community is only now starting to characterize the long-term effects of treatment on these young cancer survivors, many decades later. Mantle radiation has been implicated in significantly increased cardiovascular risks, pulmonary fibrosis, other cancers, and thyroid disease over the patient’s lifetime. However, new syndromes are still being discovered within this population as they age. The purpose of this case study was to consider the unique health issues of cancer survivors, and how their treatment history should prompt us to broaden our differentials. Our patient presented …
Pheochromocytoma With Ivc Invasion: Case Report & Systematic Review Of Literature, Jennifer Kim Bs, Ms2, Gitonga Munene M.D., David Schutter Md, Pgy3
Pheochromocytoma With Ivc Invasion: Case Report & Systematic Review Of Literature, Jennifer Kim Bs, Ms2, Gitonga Munene M.D., David Schutter Md, Pgy3
Research Day
Surgical management and outcome of pheochromocytoma with invasion of the inferior vena cava (IVC) has not been thoroughly reported or widely available in the literature. As determining the malignancy of pheochromocytoma has yet to be clearly defined and the experience of surgical resection of this condition is underrepresented, we include a case report and a systematic literature review on this condition. A literature search in PubMed was performed based on a recent review article by Kassahun et al. (2016). The search yielded 13 case reports between 1988 and 2014 from which data was extracted based on the following variables: patient’s …
Mechanical Loading As Potential Treatment For Wnt Inhibitor Induced Bone Loss, Juraj Zahatnansky Md, Daniel Dick, Gabrielle Foxa, Robert Baker, Bart Williams Phd
Mechanical Loading As Potential Treatment For Wnt Inhibitor Induced Bone Loss, Juraj Zahatnansky Md, Daniel Dick, Gabrielle Foxa, Robert Baker, Bart Williams Phd
Research Day
The Wnt signaling pathway has been shown to play a role in bone homeostasis and carcinogenesis. On the one hand, a decrease in signaling has been associated with a decrease in bone mass, on the other, an increase in signaling with cancer development. LGK974 is a Wnt signaling inhibitor currently being investigated as a potential cancer therapeutic agent. This molecule inhibits Porcupine, a transmembrane protein necessary for Wnt ligand secretion. In light of the above and based on our preliminary data, treatment with LGK974 leads to bone mass loss. Our investigation aims to address whether such bone loss can be …