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Effects Of Varying Doses Of Oral Bisphenol A Consumption On Type 2 Diabetes Risk Markers In Healthy Adults, Todd Hagobian, Alyssa Bird, Sean Stanelle, Dana Williams, Andrew Schaffner, Suzanne Phelan
Effects Of Varying Doses Of Oral Bisphenol A Consumption On Type 2 Diabetes Risk Markers In Healthy Adults, Todd Hagobian, Alyssa Bird, Sean Stanelle, Dana Williams, Andrew Schaffner, Suzanne Phelan
Kinesiology and Public Health
Objective
To determine the effects of varying doses of orally administered BPA on indices of glucose metabolism.
Methods
Eleven college students (21.0 ± 0.8 years; 24.2 ± 3.9 kg/m2) were randomized in a double-blinded, crossover fashion separated by >1 week to placebo (PL), deuterated BPA at 4 µg/kg body weight (BPA-4), and deuterated BPA at 50 µg/kg body weight (BPA-50). Total BPA, glucose, insulin, and C-peptide were assessed at baseline, minutes 15, 30, 45, 60, and every 30 minutes for 2 hours in response to a glucose tolerance test.
Results
There was a significant condition × time interaction …
Diabetes Prevalence Is Associated With Serum 25-Hydroxyvitamin D And 1,25-Dihydroxyvitamin D In Us Middle-Aged Caucasian Men And Women: A Cross-Sectional Analysis Within The Prostate, Lung, Colorectal And Ovarian Cancer Screening Trial, Kaye E. Brock, Wen-Yi Huang, David R. Fraser, Liang Ke, Marilyn Tseng, Rebecca S. Mason, Rachael Z. Stolzenberg-Solomon, D. Michal Freedman, Jiyoung Ahn, Ulrike Peters, Catherine Mccarty, Bruce W. Hollis, Regina G. Ziegler, Mark P. Purdue, Barry I. Graubard
Diabetes Prevalence Is Associated With Serum 25-Hydroxyvitamin D And 1,25-Dihydroxyvitamin D In Us Middle-Aged Caucasian Men And Women: A Cross-Sectional Analysis Within The Prostate, Lung, Colorectal And Ovarian Cancer Screening Trial, Kaye E. Brock, Wen-Yi Huang, David R. Fraser, Liang Ke, Marilyn Tseng, Rebecca S. Mason, Rachael Z. Stolzenberg-Solomon, D. Michal Freedman, Jiyoung Ahn, Ulrike Peters, Catherine Mccarty, Bruce W. Hollis, Regina G. Ziegler, Mark P. Purdue, Barry I. Graubard
Kinesiology and Public Health
Hypovitaminosis D may be associated with diabetes, hypertension and CHD. However, because studies examining the associations of all three chronic conditions with circulating 25-hydroxyvitamin D (25(0H)D) and 1,25-dihydroxyvitamin D (1,25(0H)2D) are limited, we examined these associations in the US Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial (n 2465). Caucasian PLCO participants selected as controls in previous nested case-control studies of 25(0H)D and 1,25(0H)2D were included in this analysis. Diabetes, CHD and hypertension prevalence, risk factors for these conditions and intake of vitamin D and Ca were collected from a baseline questionnaire. Results indicated …
The Role Of Adherence In Mediating The Relationship Between Depression And Health Outcomes, Rena R. Wing, Suzanne Phelan, Deborah Tate
The Role Of Adherence In Mediating The Relationship Between Depression And Health Outcomes, Rena R. Wing, Suzanne Phelan, Deborah Tate
Kinesiology and Public Health
Depression has been linked to poor health outcome in a number of studies; however, the mechanism underlying this relationship has received little attention. This paper explores the possibility that adherence mediates the relationship between depression and outcome. Principal findings regarding the relationship between depression, adherence, and outcome are reviewed. The data suggest that depression is related, at least moderately, to poorer adherence to a variety of treatment components. The relationship between adherence and outcome is more difficult to establish. In addition, current data, albeit limited, do not support the hypothesis that adherence mediates the relationship between depression and outcome. An …