Open Access. Powered by Scholars. Published by Universities.®
- Keyword
- Publication
Articles 1 - 3 of 3
Full-Text Articles in Life Sciences
Factors Influencing Primate Hair Microbiome Diversity, Catherine Kitrinos
Factors Influencing Primate Hair Microbiome Diversity, Catherine Kitrinos
Masters Theses
Primate hair is both a substrate upon which essential social interactions occur and an important host-pathogen interface. As commensal microbes provide important immune functions for their hosts, understanding the microbial diversity in primate hair could provide insight into primate immunity and disease transmission. While studies of human hair and skin microbiomes show differences in microbial communities across body regions, little is known about the nonhuman primate hair microbiome. In this study, we collected hair samples (n=159) from 8 body regions across 12 nonhuman primate species housed at 3 US institutions to examine 1) the diversity and composition of the primate …
Rapid Cell Phenotyping Using Array-Based Sensors: Applications In Cancer Stem Cell Therapy And High-Content Screening, Yingying Geng
Rapid Cell Phenotyping Using Array-Based Sensors: Applications In Cancer Stem Cell Therapy And High-Content Screening, Yingying Geng
Doctoral Dissertations
Cell surface harbors rich information regarding the status of cell health. Being able to monitor and detect its changes in response to stimuli will provide crucial information in drug discovery, disease diagnosis, and human health. Despite the efforts and breakthroughs made possible through the specific sensing approach, there are significant challenges in extracting the information on the cell surface in a quantitative and reliable way. To address this challenge, I took the approach of array-based, hypothesis-free sensing in which the engineered sensors selectively interact with target analytes, producing a distinct pattern of response that enables analyte identification. This signature-based pattern …
Caprine Γδ T Cell Biology, Alehegne W. Yirsaw
Caprine Γδ T Cell Biology, Alehegne W. Yirsaw
Doctoral Dissertations
CAPRINE gd T CELL BIOLOGY AUGUST 2020 ALEHEGNE W YIRSAW, DVM, ADDIS ABABA UNIVERSITY, ETHIOPIA MSC., ADDIS ABABA UNIVERSITY, ETHIOPIA PHD., UNIVERSITY OF MASSACHUSETTS AMHERST DIRECTED BY: PROFESSOR CYNTHIA L BALDWIN Goats are important food animals and are disseminated globally. Their productivity is impacted by infectious diseases thus impacting the livestock owners and the community. γδ T lymphocytes or T cells have vital roles in immune responses in mammals and thus we identified information gaps regarding these cells in goats. We used genome annotation, PCR amplification of genomic DNA and cDNA, and Sanger and PacBio sequencing for this research to …