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Immunology and Infectious Disease

Brigham Young University

Theses/Dissertations

1975

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Efficacy Of Bunamidine Hydrochloride Against Immature And Mature Stages Of Echinococcus Granulosus, Lauritz A. Jensen Dec 1975

Efficacy Of Bunamidine Hydrochloride Against Immature And Mature Stages Of Echinococcus Granulosus, Lauritz A. Jensen

Theses and Dissertations

A study was conducted to determine the efficacy of bunamidine hydrochloride against the immature and mature stages of Echinococcus granulosus found in Utah. Twenty-seven dogs were obtained from local animal shelters and experimentally infected with the parasite. The drug was given at dosage levels of 25 mg/kg to 50 mg/kg of bodyweight. It was from 85.9 to 98.8% effective against the immature stage, and 100% effective against the adult stage. The results suggest that this drug can feasibly be used under field conditions where hydatid disease is endemic.