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Full-Text Articles in Life Sciences

Developing A Multiplex Pcr To Amplify Borrelia Burgdorferi Dna In The Presence Of Ixodes Scapularis Dna, Mckenzie Henkelman, Kimberly Bates Apr 2021

Developing A Multiplex Pcr To Amplify Borrelia Burgdorferi Dna In The Presence Of Ixodes Scapularis Dna, Mckenzie Henkelman, Kimberly Bates

Ramaley Celebration

Lyme Disease is caused by a spirochete bacterium (Borrelia burgdorferi). It is transmitted by ticks of the genus Ixodes. Ixodes scapularis, more commonly known as the black-legged tick or deer tick is capable of carrying and transmitting the bacteria Borrelia burgdorferi to humans and other mammals and is the species of ticks found in Minnesota and Wisconsin. Lyme Disease is a complex disease that causes a multitude of side effects both acute and chronic. It can affect multiple systems in the human body, including the cardiovascular and nervous systems. The prevalence of Lyme Disease in the Midwest …


Exploring Anti-Schistosoma Analog Sa01, Sarah Alsuleiman Mar 2021

Exploring Anti-Schistosoma Analog Sa01, Sarah Alsuleiman

UNO Student Research and Creative Activity Fair

Schistosomiasis is a waterborne parasitic worm infection able to infect in the larval stage through direct skin penetration. This disease affects approximately 270 million people worldwide and is widespread in tropical as well as subtropical regions with higher distribution in areas lacking sufficient sanitation and safe drinking water. Although some possible alternatives are emerging, currently, the most effective drug treatment is praziquantel (PZQ). However, PZQ is only effective against the adult stage of the worm, allowing juvenile worms to progress in the infection. Furthermore, Schistosoma is developing resistance to this drug as reduced efficacy has been noted. As a result, …