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Full-Text Articles in Life Sciences

Human Population History At The Crossroads Of East And Southeast Asia Since 11,000 Years Ago, Tianyi Wang, Wei Wang, Guangmao Xie, Zhen Li, Xuechun Fan, Qingping Yang, Xichao Wu, Ling Qin, Fajun Li, Melinda A. Yang Jun 2021

Human Population History At The Crossroads Of East And Southeast Asia Since 11,000 Years Ago, Tianyi Wang, Wei Wang, Guangmao Xie, Zhen Li, Xuechun Fan, Qingping Yang, Xichao Wu, Ling Qin, Fajun Li, Melinda A. Yang

Biology Faculty Publications

Past human genetic diversity and migration between southern China and Southeast Asia have not been well characterized, in part due to poor preservation of ancient DNA in hot and humid regions. We sequenced 31 ancient genomes from southern China (Guangxi and Fujian), including two ∼12,000- to 10,000-year-old individuals representing the oldest humans sequenced from southern China. We discovered a deeply diverged East Asian ancestry in the Guangxi region that persisted until at least 6,000 years ago. We found that ∼9,000- to 6,000-year-old Guangxi populations were a mixture of local ancestry, southern ancestry previously sampled in Fujian, and deep Asian ancestry …


Denisovan Dna In Late Pleistocene Sediments From Baishiya Karst Cave On The Tibetan Plateau, Dongju Zhang, Huan Xia, Fahu Chen, Bo Li, Viviane Slon, Ting Cheng, Ruowei Yang, Melinda A. Yang Oct 2020

Denisovan Dna In Late Pleistocene Sediments From Baishiya Karst Cave On The Tibetan Plateau, Dongju Zhang, Huan Xia, Fahu Chen, Bo Li, Viviane Slon, Ting Cheng, Ruowei Yang, Melinda A. Yang

Biology Faculty Publications

A late Middle Pleistocene mandible from Baishiya Karst Cave (BKC) on the Tibetan Plateau has been inferred to be from a Denisovan, an Asian hominin related to Neanderthals, on the basis of an amino acid substitution in its collagen. Here we describe the stratigraphy, chronology, and mitochondrial DNA extracted from the sediments in BKC. We recover Denisovan mitochondrial DNA from sediments deposited ~100 thousand and ~60 thousand years ago (ka) and possibly as recently as ~45 ka. The long-term occupation of BKC by Denisovans suggests that they may have adapted to life at high altitudes and may have contributed such …


First Record Of The Genus Leptodactylus (Anura: Leptodactylidae) In Cuba: Leptodactylus Fragilis, A Biological Invasion?, Tomás M. Rodríguez-Cabrera, L. Yusnaviel García-Padrón, Andrés R. Acosta Galvis, Rafael O. De Sá, Roberto Alonso Bosch Aug 2018

First Record Of The Genus Leptodactylus (Anura: Leptodactylidae) In Cuba: Leptodactylus Fragilis, A Biological Invasion?, Tomás M. Rodríguez-Cabrera, L. Yusnaviel García-Padrón, Andrés R. Acosta Galvis, Rafael O. De Sá, Roberto Alonso Bosch

Biology Faculty Publications

The Neotropical genus Leptodactylus is currently represented by three species in the West Indies (Leptodactylus albilabris, Leptodactylus fallax and Leptodactylus validus). Based on morphological, acoustic and molecular evidence, we document the presence of a fourth species in the Caribbean region, Leptodactylus fragilis (Brocchi, 1877). The species was found at two localities in western Cuba, and molecular data suggest a northern South American origin, possibly Venezuela, for these populations. We discuss the potential invasive status of L. fragilis, based on its known distribution, relative abundance, behaviour and possible impacts on native species of Cuban amphibians.


Assignment Of Fragile Site 8e (Fra8e) To Human Chromosome Band 8q24.11 Adjacent To The Hereditary Multiple Exostoses 1 Gene And Two Overlapping Langer-Giedion Syndrome Deletion Endpoints, April L. Hill, Y. Harada, E. Takahashi, J. Hou, M. J. Wagner, D. E. Wells Jan 1997

Assignment Of Fragile Site 8e (Fra8e) To Human Chromosome Band 8q24.11 Adjacent To The Hereditary Multiple Exostoses 1 Gene And Two Overlapping Langer-Giedion Syndrome Deletion Endpoints, April L. Hill, Y. Harada, E. Takahashi, J. Hou, M. J. Wagner, D. E. Wells

Biology Faculty Publications

The distamycin A inducible fragile site, FRA8E, Fra(8) (q24.11) has been previously mapped to 8q24.11, proximal to the MYC gene, by fluorescent in situ hybridization (Takahasi et al., 1991). This fragile site has been shown to be present in about 1 out of every 140 healthy Japanese individuals (Takahasi et al., 1988). To more precisely map FRA8E, we have used cosmids isolated from the Langer-Giedion chromosomal region (LGCR) for FISH analysis. Langer-Giedion syndrome (LGS) is a contiguous gene syndrome characterized by chromosome deletions in Sq24.11 (Ludecke et al., 1991). One of the genes known to be involved in the etiology …