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Plant-Mediated Alteration Of The Peritrophic Matrix And Baculovirus Infection In Lepidopteran Larvae, Ruth C. Plymale, Michael J. Grove, Diana Cox-Foster, Nancy Ostiguy, Kelli Hoover
Plant-Mediated Alteration Of The Peritrophic Matrix And Baculovirus Infection In Lepidopteran Larvae, Ruth C. Plymale, Michael J. Grove, Diana Cox-Foster, Nancy Ostiguy, Kelli Hoover
Articles
The peritrophic matrix (PM) lines the midgut of most insects, providing protection to the midgut epithelial cells while permitting passage of nutrients and water. Herein, we provide evidence that plant-mediated alteration of the PM contributes to the well-documented inhibition of fatal infection by Autographa californica multiple nucleopolyhedrovirus (AcMNPV) of Heliothis virescens F. larvae fed cotton foliage. We examined the impact of the PM on pathogenesis using a viral construct expressing a reporter gene (AcMNPV-hsp70/ lacZ) orally inoculated into larvae with either intact PMs or PMs disrupted by Trichoplusia ni granulovirus occlusion bodies containing enhancin, known to degrade insect intestinal mucin. …