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Full-Text Articles in Life Sciences
Development Of Structured Delivery Systems Using Nanolaminated Biopolymer Layers, Young-Hee Cho
Development Of Structured Delivery Systems Using Nanolaminated Biopolymer Layers, Young-Hee Cho
Open Access Dissertations
The objectives of this study were to carry out research to better understand of the formation, stability and properties of multilayer emulsions containing nano-laminated biopolymer coatings, and to utilize this information to develop food-grade delivery systems. The effect of various preparation parameters on the formation and stability of multilayer emulsions was investigated: droplet concentration; mean droplet diameter; droplet charge; biopolymer concentration. β-lactoglobulin (β-Lg) stabilized emulsions (0.5 – 10 wt% oil) containing different pectin concentrations (0 to 0.5 wt%) were prepared at pH 7 (where lipid droplets and pectin molecules were both anionic) and pH 3.5 (where lipid droplets were cationic …
Fabrication Of Protein-Polysaccharide Particulates Through Thermal Treatment Of Associative Complexes, Owen Griffith Jones
Fabrication Of Protein-Polysaccharide Particulates Through Thermal Treatment Of Associative Complexes, Owen Griffith Jones
Open Access Dissertations
Mixed solutions of β-lactoglobulin and anionic polysaccharides, specifically pectin, were formed into associative complexes through pH reduction from neutral conditions. Thermal treatment of these associative complexes was investigated as a function of biopolymer composition, heating conditions, pH, and ionic strength. Thermal treatment of β-lactoglobulin-pectin complexes at pH 4.5 – 5.0 was found to create protein-based particulates of consistent and narrow size distribution (diameter ~ 150 – 400 nm). These particulates were relatively stable to further pH adjustment and to high levels of salt (200 NaCl). Particle characteristics were maintained after re-suspending them in aqueous solutions after they have been either …