Open Access. Powered by Scholars. Published by Universities.®
- Publication
Articles 1 - 6 of 6
Full-Text Articles in Life Sciences
Impact Of Fermented And Non-Fermented Plant-Based Foods Supplementation On Gut Microbiota And Metabolites In C57bl/6j Mice, Priya Darshan Gandhi
Impact Of Fermented And Non-Fermented Plant-Based Foods Supplementation On Gut Microbiota And Metabolites In C57bl/6j Mice, Priya Darshan Gandhi
Masters Theses
Plant-based proteins have gained popularity because of their high nutritional value and more sustainable alternative to animal-based proteins. Soybean and chickpea are two widely consumed plant-based proteins, whereas tempeh is a popular plant-based fermented whole food product that is rich in protein. With the increase in the development of plant-based food products, there is little research into how plant proteins affect gut microbiota characteristics and metabolites. Therefore, there is a need to understand the underlying mechanisms surrounding the consumption of these foods. The purpose of this study was to investigate the health benefits of soybean, chickpea, and their tempeh counterparts’ …
Impact Of Animal Protein And Plant Protein On The Gut Microbiota And Metabolites Of C57bl/6j Mice, Levina Soetyono
Impact Of Animal Protein And Plant Protein On The Gut Microbiota And Metabolites Of C57bl/6j Mice, Levina Soetyono
Masters Theses
Plant-derived protein has gained popularity in recent years due to its health and environmental impact. Studies comparing the health benefits of animal and plant protein have mostly focused on soy as a plant protein representative due to its popularity. Demand for other protein sources such as peas and fava beans has been increasing; thus, the health impact of plant protein sources other than soy must be assessed. Evidence has shown that diet influences the gut microbiota and the metabolites in the body. Metabolites associated with amino acids are strong contributors to the metabolite distinction between dietary animal and plant foods. …
Promotion Of Colon Health By Strawberry And Cranberry, Yanhui Han
Promotion Of Colon Health By Strawberry And Cranberry, Yanhui Han
Doctoral Dissertations
Inflammatory bowel disease (IBD) has posed serious threats to the human health, which lead to chronic malabsorption of nutrients, abnormal pain and rectal bleeding. Both genetic predisposition and environmental factors contribute to the onset of IBD. Multiple studies suggested that dysbiosis in colon plays an important role in the development of colitis, and gut microbiota composition are different between patients with IBD and healthy individuals. Intake of whole foods, such as fruits and vegetables, may confer health benefits to the host. The beneficial effects of fruits and vegetables mainly attribute to their richness of polyphenols and microbiota-accessible carbohydrates (MACs). Components …
The Catalytic Urease Subunit Urec Is Critical For Bifidobacterium Longum Urea Utilization, Yang Lyu
The Catalytic Urease Subunit Urec Is Critical For Bifidobacterium Longum Urea Utilization, Yang Lyu
Doctoral Dissertations
In the first study, we investigated the utilization of a human milk nitrogen source, urea, by Bifidobacterium. Urea accounts for ~15% in human milk, which is an abundant non-protein nitrogen (NPN). Some bifidobacteria are found to harbor urease gene clusters that potentially enable their hydrolysis of the human milk urea. However, the underlying mechanisms are still unclear. To incisively link the urease gene cluster with bifidobacterial urea utilization, chemical mutagenesis (i.e. ethyl methanesulfonate) was performed on the urease-positive Bifidobacterium longum subsp. suis UMA399. Mutants were selected on differential media and genetic lesions were identified using whole genome sequencing. …
Biotransformation Of Resveratrol And Its Implications In Biological Activities In The Colon, Fang Li
Biotransformation Of Resveratrol And Its Implications In Biological Activities In The Colon, Fang Li
Doctoral Dissertations
Resveratrol (RES) is a natural polyphenol compound with a wide range of health-promoting activities, including protective effects against colon cancer and renal disease. However, the premise of these benefits has been dampened since RES shows a poor oral bioavailability due to its rapid and extensive biotransformation after oral consumption. The paradox (low bioavailability but high bioactivity) warrants further investigations to determine the contribution of RES metabolites to the health benefits associated with RES. We identified 11 metabolites of RES in mice with high-resolution HPLC-MS/MS, then quantified two major metabolites - dihydro-resveratrol (DHR) and lunularin (LUN). To further understand the chemopreventative …
Interaction Between Dietary Components And Gut Microbiota And Its Implication In Bioactivities And Metabolism In Colon, Min Gu
Doctoral Dissertations
The microbial cells that colonize the human body, including mucosal and skin environments, are at least as abundant as our somatic cells and certainly contain far more genes than our human genome. Gut microbiota dysbiosis is associated with the onset and progress of several diseases, like diabetes, obesity, inflammatory bowel disease. One of the environmental factor-diet intervention can modulate the compositions of gut microbiota, which in turn may contribute to altered health outcomes such as changes in the risks of chronic diseases. Orange peel has been a traditional herb in China, and some of its compounds has shown health benefits. …