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Food-Grade Cationic Antimicrobial Ε-Polylysine Transiently Alters The Gut Microbial Community And Predicted Metagenome Function In Cd-1 Mice, Xiaomeng You, Jonah E. Einson, Cynthia Lyliam Lopez-Pena, Mingyue Song, Hang Xiao, David Julian Mcclements, David Sela
Food-Grade Cationic Antimicrobial Ε-Polylysine Transiently Alters The Gut Microbial Community And Predicted Metagenome Function In Cd-1 Mice, Xiaomeng You, Jonah E. Einson, Cynthia Lyliam Lopez-Pena, Mingyue Song, Hang Xiao, David Julian Mcclements, David Sela
Food Science Department Faculty Publication Series
Diet is an important factor influencing the composition and function of the gut microbiome, but the effect of antimicrobial agents present within foods is currently not understood. In this study, we investigated the effect of the food-grade cationic antimicrobial ε-polylysine on the gut microbiome structure and predicted metagenomic function in a mouse model. The relative abundances of predominant phyla and genera, as well as the overall community structure, were perturbed in response to the incorporation of dietary ε-polylysine. Unexpectedly, this modification to the gut microbiome was experienced transiently and resolved to the initial basal composition at the final sampling point. …