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Effects Of Conjugated Linoleic Acid (Cla) On Skeletal Muscle Metabolism, Yoo Kim

Doctoral Dissertations

Although it is well known that increased physical activity can help reduce incidences of obesity, physical activity can be influenced by complex issues, making it difficult to use universal means to control obesity. Recent discoveries of the effects of exercise at the cellular level opened up the unique opportunity to develop compounds with ‘exercise-like’ effects. In fact, CLA has been shown to promote voluntary activity and endurance capacity in mice. Thus, the purpose of these studies is to determine the mechanisms of conjugated linoleic acid on muscle metabolism via the modulation of biochemical events including mitochondrial biogenesis and the alternation …