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Lipoprotein Discordance: Associations With Diabetes, Metabolic Syndrome, And Response To Exercise, Jonathan Joseph Pulama Kupaianaha Ruiz-Ramie
Lipoprotein Discordance: Associations With Diabetes, Metabolic Syndrome, And Response To Exercise, Jonathan Joseph Pulama Kupaianaha Ruiz-Ramie
Theses and Dissertations
Purpose: To compare baseline CVD risk factor profiles among groups of individuals with discordant levels of high- and low-density lipoprotein cholesterol (HDL-C and LDL-C respectively) compared to lipoprotein particle concentration (HDL-P and LDL-P respectively) and examine the associations between lipoprotein discordance and incident type 2 diabetes mellitus (T2D) and metabolic syndrome (MetS). Furthermore, to examine the association between lipoprotein discordance and exercise induced changes in CVD risk factors.
Methods: Standard lipid panels as well as lipoprotein subclass profiles via nuclear magnetic resonance spectroscopy were measured among three previously completed studies (CARDIA cohort, HERITAGE Family Study, and HART-D study) spanning over …